Program Pr-124

Genes (58)

BDKRB1, TFPI2, IL1A, MMP8, EREG, CYP19A1, SPINK1, CST7, TLR8, NKG7, CD2, KMO, PTPN22, HK3, GCKR, CD226, CXCL3, FAP, CD40, CD3D, CCL5, LAMP3, SOCS1, IKBKE, ACPP, CCR7, STX11, IL1RN, CIITA, CR1, SH2D2A, DGKA, SLC7A8, PTGER2, KLF4, STRA6, VENTX, CXCL1, GPR171, CXCL2, RNASE4, PLEK2, PERP, TNFSF4, RAB38, KRT7, RHOD, STAP2, PSTPIP2, IL15, CFD, DAPP1, SIGLEC1, EBI3, UNC93B1, CTSW, CD7, CASP5

Regulons (18)

R-271, R-284, R-1313, R-1618, R-1922, R-2137, R-2140, R-2677, R-2836, R-2879, R-3021, R-3101, R-3130, R-3300, R-3524, R-3555, R-3629, R-3708

Regulons in program Pr-124

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-271	2.0995	7	16
R-284	1.58903	7	8
R-1313	2.2117	9	18
R-1618	1.71576	6	13
R-1922	1.65822	7	10
R-2137	1.94198	8	12
R-2140	1.62934	6	11
R-2677	1.97664	6	28
R-2836	2.28242	9	19
R-2879	2.80675	7	6
R-3021	2.03204	9	19
R-3101	1.14034	7	23
R-3130	1.49098	9	10
R-3300	1.69207	5	16
R-3524	1.43453	6	6
R-3555	2.00044	7	7
R-3629	2.6776	7	21
R-3708	2.71698	5	8

Genes in program Pr-124

EnsEMBL Id	Entrez Id	Preferred
ENSG00000100739	623	BDKRB1
ENSG00000105825	7980	TFPI2
ENSG00000115008	3552	IL1A
ENSG00000118113	4317	MMP8
ENSG00000124882	2069	EREG
ENSG00000137869	1588	CYP19A1
ENSG00000164266	6690	SPINK1
ENSG00000077984	8530	CST7
ENSG00000101916	51311	TLR8
ENSG00000105374	4818	NKG7
ENSG00000116824	914	CD2
ENSG00000117009	8564	KMO
ENSG00000134242	26191	PTPN22
ENSG00000160883	3101	HK3
ENSG00000084734	2646	GCKR
ENSG00000150637	10666	CD226
ENSG00000163734	2921	CXCL3
ENSG00000078098	2191	FAP
ENSG00000101017	958	CD40
ENSG00000167286	915	CD3D
ENSG00000274233	6352	CCL5
ENSG00000078081	27074	LAMP3
ENSG00000185338	8651	SOCS1
ENSG00000263528	9641	IKBKE
ENSG00000014257	55	ACPP
ENSG00000126353	1236	CCR7
ENSG00000135604	8676	STX11
ENSG00000136689	3557	IL1RN
ENSG00000179583	4261	CIITA
ENSG00000203710	1378	CR1
ENSG00000027869	9047	SH2D2A
ENSG00000065357	1606	DGKA
ENSG00000092068	23428	SLC7A8
ENSG00000125384	5732	PTGER2
ENSG00000136826	9314	KLF4
ENSG00000137868	64220	STRA6
ENSG00000151650	27287	VENTX
ENSG00000163739	2919	CXCL1
ENSG00000174946	29909	GPR171
ENSG00000081041	2920	CXCL2
ENSG00000258818	6038	RNASE4
ENSG00000100558	26499	PLEK2
ENSG00000112378	64065	PERP
ENSG00000117586	7292	TNFSF4
ENSG00000123892	23682	RAB38
ENSG00000135480	3855	KRT7
ENSG00000173156	29984	RHOD
ENSG00000178078	55620	STAP2
ENSG00000152229	9050	PSTPIP2
ENSG00000164136	3600	IL15
ENSG00000274619	1675	CFD
ENSG00000070190	27071	DAPP1
ENSG00000088827	6614	SIGLEC1
ENSG00000105246	10148	EBI3
ENSG00000110057	81622	UNC93B1
ENSG00000172543	1521	CTSW
ENSG00000173762	924	CD7
ENSG00000137757	838	CASP5

Causal Mechanistic Flows with Program Pr-124

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-01406	UGGT1	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-03004	SPEF2	up-regulates	BPTF	represses	R-2879	21	3	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BERMEKIMAB, LUTIKIZUMAB
CMF-03007	SPEF2	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-04016	DSP	up-regulates	FOXG1	represses	R-2836	13	6	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-04180	RBPJL	down-regulates	LHX2	represses	R-3708	7	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-04504	LAMC3	up-regulates	LHX2	represses	R-3708	7	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-05306	PCSK6	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-05610	GRM6	up-regulates	LHX2	represses	R-3708	7	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-05625	GRM6	up-regulates	FOXG1	represses	R-2836	13	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-06048	OTOA	down-regulates	SPIB	activates	R-3629	4	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-06311	AFF2	up-regulates	FOXG1	represses	R-2836	13	6	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-06514	SETD2	up-regulates	LHX2	represses	R-3708	7	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-06531	SETD2	down-regulates	SPIB	activates	R-3629	4	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-06654	SCNN1G	up-regulates	FOXG1	represses	R-2836	13	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-07574	AHNAK2	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-08073	TRIM6-TRIM34	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-10158	ANK2	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-11585	DNAH7	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-11685	AHR	up-regulates	FOXG1	represses	R-2836	13	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-12813	HOXA6	up-regulates	FOXG1	represses	R-2836	13	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-13887	HRH2	down-regulates	LHX2	represses	R-3708	7	2	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-14732	BCOR	up-regulates	FOXG1	represses	R-2836	13	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-15009	TG	up-regulates	BPTF	represses	R-2879	21	4	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BERMEKIMAB, LUTIKIZUMAB
CMF-15032	TG	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-15499	ZFP57	up-regulates	FOXG1	represses	R-2836	13	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-15853	ZNF845	down-regulates	SPIB	activates	R-3629	4	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-17395	TBC1D8	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-17777	C3	down-regulates	SPIB	activates	R-3629	4	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-18018	PRPF40B	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-18899	INPP5J	up-regulates	FOXG1	represses	R-2836	13	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-19208	NF1	down-regulates	LHX2	represses	R-3708	7	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-19614	BRCA1	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-21792	COL1A2	up-regulates	FOXG1	represses	R-2836	13	4	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-22196	PODXL	up-regulates	BPTF	represses	R-2879	21	1	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BERMEKIMAB, LUTIKIZUMAB
CMF-22411	IDH1	up-regulates	BPTF	represses	R-2879	21	10	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BERMEKIMAB, LUTIKIZUMAB
CMF-22721	IDH1	down-regulates	SPIB	activates	R-3629	4	4	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-23044	AOX1	up-regulates	BPTF	represses	R-2879	21	2	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BERMEKIMAB, LUTIKIZUMAB
CMF-23053	AOX1	down-regulates	SPIB	activates	R-3629	4	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-23686	TP53	up-regulates	BPTF	represses	R-2879	21	11	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BERMEKIMAB, LUTIKIZUMAB
CMF-24242	OR5K1	up-regulates	FOXG1	represses	R-2836	13	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-24411	EPHA10	up-regulates	FOXG1	represses	R-2836	13	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-25096	IQSEC3	up-regulates	FOXG1	represses	R-2836	13	6	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-25558	ZNF727	up-regulates	LHX2	represses	R-3708	7	2	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-25658	SVOPL	up-regulates	FOXG1	represses	R-2836	13	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-26219	CARD11	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-26752	RB1	up-regulates	SPIB	activates	R-3629	4	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-27152	SLC44A5	up-regulates	FOXG1	represses	R-2836	13	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-28509	ACSM4	up-regulates	FOXG1	represses	R-2836	13	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-28550	SNTG2	down-regulates	SPIB	activates	R-3629	4	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-28960	NPHS1	up-regulates	FOXG1	represses	R-2836	13	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-30436	DVL2	up-regulates	FOXG1	represses	R-2836	13	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-30770	ZDBF2	up-regulates	LHX2	represses	R-3708	7	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-30861	L1CAM	up-regulates	FOXG1	represses	R-2836	13	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-31149	LRFN2	down-regulates	SPIB	activates	R-3629	4	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BERMEKIMAB, LUTIKIZUMAB, EMRICASAN
CMF-33921	MYO7B	down-regulates	hsa-mir-454-3p	represses	R-2836	31	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-33923	MYO7B	down-regulates	hsa-mir-98	represses	R-2836	8	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-33926	MYO7B	down-regulates	hsa-mir-301	represses	R-2836	37	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-34076	ACAN	up-regulates	hsa-mir-454-3p	represses	R-2836	31	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-34078	ACAN	up-regulates	hsa-mir-363	represses	R-2836	19	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-34879	ZFYVE26	up-regulates	hsa-mir-363	represses	R-2836	19	6	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-34962	ADAMTS19	up-regulates	hsa-mir-363	represses	R-2836	19	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-35061	FGFR3	down-regulates	hsa-mir-454-3p	represses	R-2836	31	29	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-35280	ATRX	up-regulates	hsa-mir-454-3p	represses	R-2836	31	22	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-35360	ATRX	up-regulates	hsa-mir-98	represses	R-2836	8	8	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-35382	ATRX	up-regulates	hsa-mir-301	represses	R-2836	37	32	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-36250	PLEKHG4B	up-regulates	hsa-mir-301	represses	R-2836	37	5	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-36962	PKD1L2	up-regulates	hsa-mir-301	represses	R-2836	37	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-37235	FNDC3B	up-regulates	hsa-mir-149	represses	R-2836	51	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-37403	SIN3A	up-regulates	hsa-mir-454-3p	represses	R-2836	31	4	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-37421	HOXA6	up-regulates	hsa-mir-301	represses	R-2836	37	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-38554	TBX5	down-regulates	hsa-mir-301	represses	R-2836	37	4	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-38910	ODZ1	up-regulates	hsa-mir-423	represses	R-2836	3	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-39336	DENND1C	up-regulates	hsa-mir-454-3p	represses	R-2836	31	4	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-39339	DENND1C	up-regulates	hsa-mir-98	represses	R-2836	8	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-39834	UGT2B4	down-regulates	hsa-mir-149	represses	R-2836	51	35	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-39846	AGAP6	up-regulates	hsa-mir-454-3p	represses	R-2836	31	5	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-39849	ZNF658	up-regulates	hsa-mir-454-3p	represses	R-2836	31	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-40143	KRTAP4-7	down-regulates	hsa-mir-423	represses	R-2836	3	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-40261	COL22A1	up-regulates	hsa-mir-454-3p	represses	R-2836	31	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-40375	MRGPRE	up-regulates	hsa-mir-149	represses	R-2836	51	12	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-40524	IDH1	up-regulates	hsa-mir-454-3p	represses	R-2836	31	22	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-40682	IDH1	up-regulates	hsa-mir-98	represses	R-2836	8	8	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-40704	IDH1	up-regulates	hsa-mir-301	represses	R-2836	37	32	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-41613	EPHA10	up-regulates	hsa-mir-454-3p	represses	R-2836	31	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-41766	IQSEC3	up-regulates	hsa-mir-423	represses	R-2836	3	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-41784	IQSEC3	up-regulates	hsa-mir-454-3p	represses	R-2836	31	25	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-41859	IQSEC3	up-regulates	hsa-mir-98	represses	R-2836	8	7	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-41990	KSR2	up-regulates	hsa-mir-454-3p	represses	R-2836	31	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-41993	MYO18B	up-regulates	hsa-mir-363	represses	R-2836	19	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-42102	MST1P9	up-regulates	hsa-mir-301	represses	R-2836	37	4	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-42580	RAB11FIP1	up-regulates	hsa-mir-454-3p	represses	R-2836	31	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-42611	KRTAP4-8	up-regulates	hsa-mir-423	represses	R-2836	3	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-42684	IFT172	up-regulates	hsa-mir-454-3p	represses	R-2836	31	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-42690	IFT172	up-regulates	hsa-mir-301	represses	R-2836	37	7	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-42789	AQP10	up-regulates	hsa-mir-301	represses	R-2836	37	10	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-42842	UHRF1BP1L	up-regulates	hsa-mir-423	represses	R-2836	3	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-43244	CYP2B6	up-regulates	hsa-mir-149	represses	R-2836	51	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-43245	CYP2B6	up-regulates	hsa-mir-98	represses	R-2836	8	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-43262	ABCA13	up-regulates	hsa-mir-363	represses	R-2836	19	1	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-43316	LRRC55	up-regulates	hsa-mir-149	represses	R-2836	51	2	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG
CMF-43334	LRFN2	up-regulates	hsa-mir-423	represses	R-2836	3	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALPROSTADIL, DINOPROSTONE, EVATANEPAG, OMIDENEPAG

Program

Pr-124

Program Pr-124

Genes (58)

Regulons (18)

Regulons in program Pr-124

Genes in program Pr-124

Causal Mechanistic Flows with Program Pr-124

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Regulon Drugs (3)

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