Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

CXCL3 - C-X-C motif chemokine ligand 3

Function

Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
2921 ENSG00000163734 CXCL3 P19876

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1731Pr-30118
R-2343Pr-30119
R-2632Pr-301113
R-3070Pr-30118