Program Pr-28

Genes (7)

PLAUR, SERPINE1, CTSC, SH3BGRL3, ITGA5, IGFBP6, PRSS23

Regulons (10)

R-157, R-245, R-1895, R-2331, R-2601, R-2765, R-2781, R-3029, R-3131, R-3571

Regulons in program Pr-28

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-157	3.37706	6	13
R-245	3.30264	5	25
R-1895	2.70573	6	1
R-2331	2.98079	5	6
R-2601	2.99043	7	8
R-2765	3.01948	6	10
R-2781	2.48907	5	3
R-3029	2.99043	7	15
R-3131	2.99043	7	6
R-3571	3.10274	5	4

Genes in program Pr-28

EnsEMBL Id	Entrez Id	Preferred
ENSG00000011422	5329	PLAUR
ENSG00000106366	5054	SERPINE1
ENSG00000109861	1075	CTSC
ENSG00000142669	83442	SH3BGRL3
ENSG00000161638	3678	ITGA5
ENSG00000167779	3489	IGFBP6
ENSG00000150687	11098	PRSS23

Causal Mechanistic Flows with Program Pr-28

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-00682	HMCN1	up-regulates	PRDM1	activates	R-157	21	16	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-00765	TPTE2	up-regulates	POU4F1	represses	R-2765	11	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-01922	PCDH9	up-regulates	NR2F1	represses	R-2781	15	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-01929	PCDH9	down-regulates	PPARG	activates	R-2331	15	4	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ALEPLASININ, BRENSOCATIB
CMF-01975	PCDH9	down-regulates	ELF4	activates	R-3029	20	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-01979	PCDH9	down-regulates	VDR	activates	R-245	14	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-03095	LAMA3	down-regulates	CEBPA	activates	R-2601	21	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-03097	LAMA3	down-regulates	PRDM1	activates	R-157	21	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-03406	CCDC60	down-regulates	ELF4	activates	R-3029	20	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-04627	CYP4F12	down-regulates	CDX1	activates	R-3131	7	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-04669	RUSC2	down-regulates	PPARG	activates	R-2331	15	2	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ALEPLASININ, BRENSOCATIB
CMF-04808	SLC6A3	down-regulates	VDR	activates	R-245	14	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-04958	ABCC5	down-regulates	VDR	activates	R-245	14	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-05173	PLA2G4A	down-regulates	VDR	activates	R-245	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-05178	XIRP2	down-regulates	PRDM1	activates	R-157	21	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-05750	ADAMTS19	down-regulates	CDX1	activates	R-3131	7	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-05780	ADAMTS19	down-regulates	VDR	activates	R-245	14	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-06816	ATRX	up-regulates	POU4F1	represses	R-2765	11	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-06960	ATRX	up-regulates	NEUROD1	represses	R-3571	5	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-07032	ATRX	down-regulates	ELF4	activates	R-3029	20	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-07041	ATRX	down-regulates	VDR	activates	R-245	14	7	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-07692	PLCXD3	down-regulates	PRDM1	activates	R-157	21	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-07722	TRPM2	down-regulates	ELF4	activates	R-3029	20	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-09280	RP1	down-regulates	ELF4	activates	R-3029	20	8	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-09282	RP1	down-regulates	VDR	activates	R-245	14	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-10015	ATP8A2	down-regulates	CDX1	activates	R-3131	7	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-10078	ATP8A2	down-regulates	CEBPA	activates	R-2601	21	7	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-11145	MYO18A	down-regulates	CEBPA	activates	R-2601	21	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-12336	GPR98	down-regulates	ELF4	activates	R-3029	20	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-12339	GPR98	down-regulates	PRDM1	activates	R-157	21	8	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-12347	GPR98	down-regulates	VDR	activates	R-245	14	8	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-12466	BPTF	up-regulates	NR2F1	represses	R-2781	15	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-12772	NTN4	down-regulates	VDR	activates	R-245	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-13047	AKD1	down-regulates	PPARG	activates	R-2331	15	2	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ALEPLASININ, BRENSOCATIB
CMF-13282	SULF2	down-regulates	VDR	activates	R-245	14	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-13759	ADAMTS8	down-regulates	PPARG	activates	R-2331	15	7	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ALEPLASININ, BRENSOCATIB
CMF-13838	ADAMTS8	down-regulates	CEBPA	activates	R-2601	21	6	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-13842	ADAMTS8	down-regulates	ELF4	activates	R-3029	20	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-13848	ADAMTS8	down-regulates	VDR	activates	R-245	14	6	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-15054	PTEN	up-regulates	ELF4	activates	R-3029	20	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-15221	OR51F1	down-regulates	CEBPA	activates	R-2601	21	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-16661	DNAJC11	down-regulates	POU4F1	represses	R-2765	11	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-17907	CYLC2	down-regulates	PRDM1	activates	R-157	21	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-17908	CYLC2	down-regulates	VDR	activates	R-245	14	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-19278	NF1	down-regulates	POU4F1	represses	R-2765	11	7	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-19491	NF1	up-regulates	ELF4	activates	R-3029	20	14	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-19497	NF1	up-regulates	PRDM1	activates	R-157	21	16	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-19641	RPSAP58	down-regulates	POU4F1	represses	R-2765	11	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-19839	FPR2	down-regulates	PPARG	activates	R-2331	15	1	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ALEPLASININ, BRENSOCATIB
CMF-19907	PAPPA2	down-regulates	PRDM1	activates	R-157	21	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-20534	ADCY1	down-regulates	NR2F1	represses	R-2781	15	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-20601	ADCY1	up-regulates	VDR	activates	R-245	14	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-21033	KRTAP4-7	down-regulates	POU4F1	represses	R-2765	11	6	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-21068	KRTAP4-7	up-regulates	ELF4	activates	R-3029	20	8	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-21142	ZNF208	down-regulates	CDX1	activates	R-3131	7	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-21466	IL4R	down-regulates	VDR	activates	R-245	14	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-21689	MUC17	up-regulates	CEBPA	activates	R-2601	21	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-21700	MUC17	up-regulates	ELF4	activates	R-3029	20	9	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-21902	PRAME	down-regulates	NEUROD1	represses	R-3571	5	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-22116	OR2T34	down-regulates	VDR	activates	R-245	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-22161	PDGFRA	down-regulates	VDR	activates	R-245	14	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-22460	IDH1	up-regulates	POU4F1	represses	R-2765	11	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-22631	IDH1	up-regulates	NEUROD1	represses	R-3571	5	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-22761	IDH1	down-regulates	ELF4	activates	R-3029	20	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-22767	IDH1	down-regulates	PRDM1	activates	R-157	21	18	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-22792	IDH1	down-regulates	VDR	activates	R-245	14	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-23084	PDHA2	down-regulates	ELF4	activates	R-3029	20	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-23085	PDHA2	down-regulates	VDR	activates	R-245	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-23732	TP53	up-regulates	POU4F1	represses	R-2765	11	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-23939	TP53	down-regulates	CEBPA	activates	R-2601	21	12	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-24875	NSUN5	down-regulates	ELF4	activates	R-3029	20	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-25072	IQSEC3	down-regulates	VDR	activates	R-245	14	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-25344	PARG	down-regulates	PRDM1	activates	R-157	21	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-25348	PARG	down-regulates	VDR	activates	R-245	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-25768	FZD10	down-regulates	CDX1	activates	R-3131	7	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-25791	FZD10	down-regulates	PRDM1	activates	R-157	21	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-26650	C5AR1	down-regulates	VDR	activates	R-245	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-26990	HMCN1	down-regulates	POU4F1	represses	R-2765	11	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-28051	CELSR3	down-regulates	CDX1	activates	R-3131	7	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-28063	CELSR3	down-regulates	PPARG	activates	R-2331	15	3	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ALEPLASININ, BRENSOCATIB
CMF-28064	CELSR3	up-regulates	POU4F1	represses	R-2765	11	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-28099	CELSR3	down-regulates	PRDM1	activates	R-157	21	8	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-28104	CELSR3	down-regulates	VDR	activates	R-245	14	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-28222	REPIN1	down-regulates	NEUROD1	represses	R-3571	5	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-28436	MYO9B	down-regulates	VDR	activates	R-245	14	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-28661	PCNX	down-regulates	VDR	activates	R-245	14	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-28740	SYN3	down-regulates	ELF4	activates	R-3029	20	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-30369	RNF130	up-regulates	IKZF2	represses	R-1895	16	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-30384	RNF130	down-regulates	CEBPA	activates	R-2601	21	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-30493	PROKR2	down-regulates	VDR	activates	R-245	14	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-30648	SALL4	down-regulates	PRDM1	activates	R-157	21	7	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34351	ADCY5	down-regulates	hsa-mir-328	represses	R-157	27	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34352	ADCY5	down-regulates	hsa-mir-328	represses	R-245	27	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34353	ADCY5	down-regulates	hsa-mir-328	represses	R-3571	27	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34530	RBPJL	down-regulates	hsa-mir-328	represses	R-157	27	9	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34531	RBPJL	down-regulates	hsa-mir-328	represses	R-2601	27	9	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34532	RBPJL	down-regulates	hsa-mir-328	represses	R-2765	27	9	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34533	RBPJL	down-regulates	hsa-mir-328	represses	R-2781	27	9	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34535	RBPJL	down-regulates	hsa-mir-328	represses	R-3029	27	9	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34536	RBPJL	down-regulates	hsa-mir-328	represses	R-3131	27	9	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34537	RBPJL	down-regulates	hsa-mir-328	represses	R-1895	27	9	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34581	MEN1	down-regulates	hsa-mir-328	represses	R-2781	27	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34935	NDST4	down-regulates	hsa-mir-328	represses	R-2781	27	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34952	ADAMTS19	up-regulates	hsa-mir-328	represses	R-157	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34953	ADAMTS19	up-regulates	hsa-mir-328	represses	R-245	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34954	ADAMTS19	up-regulates	hsa-mir-328	represses	R-2601	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34955	ADAMTS19	up-regulates	hsa-mir-328	represses	R-2765	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34956	ADAMTS19	up-regulates	hsa-mir-328	represses	R-2781	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34957	ADAMTS19	up-regulates	hsa-mir-328	represses	R-3029	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34958	ADAMTS19	up-regulates	hsa-mir-328	represses	R-3131	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34959	ADAMTS19	up-regulates	hsa-mir-328	represses	R-3571	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-34960	ADAMTS19	up-regulates	hsa-mir-328	represses	R-1895	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-37853	PRKCD	up-regulates	hsa-mir-328	represses	R-157	27	22	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-37854	PRKCD	up-regulates	hsa-mir-328	represses	R-245	27	22	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-37855	PRKCD	up-regulates	hsa-mir-328	represses	R-2601	27	22	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-37856	PRKCD	up-regulates	hsa-mir-328	represses	R-2765	27	22	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-37858	PRKCD	up-regulates	hsa-mir-328	represses	R-3029	27	22	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-37859	PRKCD	up-regulates	hsa-mir-328	represses	R-3131	27	22	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-37860	PRKCD	up-regulates	hsa-mir-328	represses	R-3571	27	22	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-37861	PRKCD	up-regulates	hsa-mir-328	represses	R-1895	27	22	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38026	PTEN	down-regulates	hsa-mir-328	represses	R-157	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38027	PTEN	down-regulates	hsa-mir-328	represses	R-245	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38028	PTEN	down-regulates	hsa-mir-328	represses	R-2601	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38029	PTEN	down-regulates	hsa-mir-328	represses	R-2765	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38030	PTEN	down-regulates	hsa-mir-328	represses	R-2781	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38032	PTEN	down-regulates	hsa-mir-328	represses	R-3029	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38033	PTEN	down-regulates	hsa-mir-328	represses	R-3131	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38034	PTEN	down-regulates	hsa-mir-328	represses	R-3571	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38035	PTEN	down-regulates	hsa-mir-328	represses	R-1895	27	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38943	HERC2	down-regulates	hsa-mir-328	represses	R-2781	27	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-38944	HERC2	down-regulates	hsa-mir-328	represses	R-1895	27	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-43273	POLRMT	down-regulates	hsa-mir-328	represses	R-157	27	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-43274	POLRMT	down-regulates	hsa-mir-328	represses	R-245	27	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-43275	POLRMT	down-regulates	hsa-mir-328	represses	R-2601	27	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-43276	POLRMT	down-regulates	hsa-mir-328	represses	R-2765	27	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-43277	POLRMT	down-regulates	hsa-mir-328	represses	R-2781	27	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-43278	POLRMT	down-regulates	hsa-mir-328	represses	R-3029	27	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-43279	POLRMT	down-regulates	hsa-mir-328	represses	R-3131	27	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-43280	POLRMT	down-regulates	hsa-mir-328	represses	R-3571	27	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB
CMF-43281	POLRMT	down-regulates	hsa-mir-328	represses	R-1895	27	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ATN-161, ALEPLASININ, BRENSOCATIB, PF-04605412, VOLOCIXIMAB

Program

Pr-28

Program Pr-28

Genes (7)

Regulons (10)

Regulons in program Pr-28

Genes in program Pr-28

Causal Mechanistic Flows with Program Pr-28

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