| CMF-15046 | PTEN | up-regulates | RXRA | activates | R-3213 | 13 | 1 | Drugs (12) Regulator Drugs (2)SDX-101, DANTHRON Regulon Drugs (10)SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, BHQ-880, ABITUZUMAB |
| CMF-15047 | PTEN | up-regulates | MAFB | activates | R-1917 | 25 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-15048 | PTEN | up-regulates | SREBF1 | activates | R-2503 | 12 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-15051 | PTEN | up-regulates | NR3C2 | activates | R-2018 | 2 | 1 | Drugs (3) |
| CMF-15054 | PTEN | up-regulates | ELF4 | activates | R-3029 | 20 | 2 | Drugs (5) |
| CMF-15056 | PTEN | up-regulates | NFATC4 | activates | R-2707 | 10 | 1 | Drugs (4) |
| CMF-38025 | PTEN | down-regulates | hsa-mir-346 | represses | R-378 | 20 | 1 | Drugs (7) |
| CMF-38026 | PTEN | down-regulates | hsa-mir-328 | represses | R-157 | 27 | 10 | Drugs (5) |
| CMF-38027 | PTEN | down-regulates | hsa-mir-328 | represses | R-245 | 27 | 10 | Drugs (5) |
| CMF-38028 | PTEN | down-regulates | hsa-mir-328 | represses | R-2601 | 27 | 10 | Drugs (5) |
| CMF-38029 | PTEN | down-regulates | hsa-mir-328 | represses | R-2765 | 27 | 10 | Drugs (5) |
| CMF-38030 | PTEN | down-regulates | hsa-mir-328 | represses | R-2781 | 27 | 10 | Drugs (5) |
| CMF-38031 | PTEN | down-regulates | hsa-mir-328 | represses | R-2945 | 27 | 10 | Drugs (7) |
| CMF-38032 | PTEN | down-regulates | hsa-mir-328 | represses | R-3029 | 27 | 10 | Drugs (5) |
| CMF-38033 | PTEN | down-regulates | hsa-mir-328 | represses | R-3131 | 27 | 10 | Drugs (5) |
| CMF-38034 | PTEN | down-regulates | hsa-mir-328 | represses | R-3571 | 27 | 10 | Drugs (5) |
| CMF-38035 | PTEN | down-regulates | hsa-mir-328 | represses | R-1895 | 27 | 10 | Drugs (5) |
| CMF-38036 | PTEN | down-regulates | hsa-mir-636 | represses | R-1598 | 1 | 1 | Drugs (52) Regulator Drugs (0)Regulon Drugs (52)TERODILINE, ACAMPROSATE CALCIUM, MIRDAMETINIB, AV-101, BINIMETINIB, MEMANTINE, DEXTROMETHORPHAN HYDROBROMIDE, COBIMETINIB FUMARATE, RO-4987655, MEMANTINE HYDROCHLORIDE, COBIMETINIB, ORPHENADRINE HYDROCHLORIDE, WX-554, AZD-8330, SELUMETINIB SULFATE, PIMASERTIB, SELUMETINIB, NERAMEXANE, KETAMINE, E-6201, DEXTROMETHORPHAN POLISTIREX, DEXTROMETHORPHAN, SAMALIZUMAB, ORPHENADRINE, TRAMETINIB, GABAPENTIN ENACARBIL, FELBAMATE, AMANTADINE HYDROCHLORIDE, PREGABALIN, RAPASTINEL, ATAGABALIN, GABAPENTIN, LANICEMINE, ACAMPROSATE, REFAMETINIB, RALFINAMIDE, BEPRIDIL, SULOCTIDIL, GW468816, NERAMEXANE MESYLATE, IMAGABALIN, ORPHENADRINE CITRATE, APIMOSTINEL, CI-1040, ESKETAMINE, INDANTADOL, ESKETAMINE HYDROCHLORIDE, AMANTADINE, TRAMETINIB DIMETHYL SULFOXIDE, KETAMINE HYDROCHLORIDE, TAK-733, AS-703988 |
| CMF-38037 | PTEN | down-regulates | hsa-mir-488 | represses | R-2402 | 19 | 1 | Drugs (1) |
| CMF-38038 | PTEN | down-regulates | hsa-mir-32 | represses | R-1598 | 1 | 1 | Drugs (52) Regulator Drugs (0)Regulon Drugs (52)TERODILINE, ACAMPROSATE CALCIUM, MIRDAMETINIB, AV-101, BINIMETINIB, MEMANTINE, DEXTROMETHORPHAN HYDROBROMIDE, COBIMETINIB FUMARATE, RO-4987655, MEMANTINE HYDROCHLORIDE, COBIMETINIB, ORPHENADRINE HYDROCHLORIDE, WX-554, AZD-8330, SELUMETINIB SULFATE, PIMASERTIB, SELUMETINIB, NERAMEXANE, KETAMINE, E-6201, DEXTROMETHORPHAN POLISTIREX, DEXTROMETHORPHAN, SAMALIZUMAB, ORPHENADRINE, TRAMETINIB, GABAPENTIN ENACARBIL, FELBAMATE, AMANTADINE HYDROCHLORIDE, PREGABALIN, RAPASTINEL, ATAGABALIN, GABAPENTIN, LANICEMINE, ACAMPROSATE, REFAMETINIB, RALFINAMIDE, BEPRIDIL, SULOCTIDIL, GW468816, NERAMEXANE MESYLATE, IMAGABALIN, ORPHENADRINE CITRATE, APIMOSTINEL, CI-1040, ESKETAMINE, INDANTADOL, ESKETAMINE HYDROCHLORIDE, AMANTADINE, TRAMETINIB DIMETHYL SULFOXIDE, KETAMINE HYDROCHLORIDE, TAK-733, AS-703988 |
| CMF-38039 | PTEN | down-regulates | hsa-mir-641 | represses | R-378 | 8 | 2 | Drugs (7) |
| CMF-38040 | PTEN | down-regulates | hsa-mir-641 | represses | R-1598 | 8 | 2 | Drugs (52) Regulator Drugs (0)Regulon Drugs (52)TERODILINE, ACAMPROSATE CALCIUM, MIRDAMETINIB, AV-101, BINIMETINIB, MEMANTINE, DEXTROMETHORPHAN HYDROBROMIDE, COBIMETINIB FUMARATE, RO-4987655, MEMANTINE HYDROCHLORIDE, COBIMETINIB, ORPHENADRINE HYDROCHLORIDE, WX-554, AZD-8330, SELUMETINIB SULFATE, PIMASERTIB, SELUMETINIB, NERAMEXANE, KETAMINE, E-6201, DEXTROMETHORPHAN POLISTIREX, DEXTROMETHORPHAN, SAMALIZUMAB, ORPHENADRINE, TRAMETINIB, GABAPENTIN ENACARBIL, FELBAMATE, AMANTADINE HYDROCHLORIDE, PREGABALIN, RAPASTINEL, ATAGABALIN, GABAPENTIN, LANICEMINE, ACAMPROSATE, REFAMETINIB, RALFINAMIDE, BEPRIDIL, SULOCTIDIL, GW468816, NERAMEXANE MESYLATE, IMAGABALIN, ORPHENADRINE CITRATE, APIMOSTINEL, CI-1040, ESKETAMINE, INDANTADOL, ESKETAMINE HYDROCHLORIDE, AMANTADINE, TRAMETINIB DIMETHYL SULFOXIDE, KETAMINE HYDROCHLORIDE, TAK-733, AS-703988 |
| CMF-38041 | PTEN | down-regulates | hsa-mir-502 | represses | R-597 | 1 | 1 | Drugs (65) Regulator Drugs (0)Regulon Drugs (65)ERIBULIN MESYLATE, SAGOPILONE, AGS-16C3F, TELISOTUZUMAB VEDOTIN, DOCETAXEL, FOSBRETABULIN DISODIUM, VINCRISTINE, VINFLUNINE, LEXIBULIN, VINCRISTINE SULFATE, TRASTUZUMAB EMTANSINE, ENFORTUMAB VEDOTIN, VINORELBINE TARTRATE, LIFASTUZUMAB VEDOTIN, KOS-1584, PRALUZATAMAB RAVTANSINE, LADIRATUZUMAB VEDOTIN, PACLITAXEL, CROLIBULIN, PACLITAXEL POLIGLUMEX, PATUPILONE, ASG-5ME, ANG1005, PINATUZUMAB VEDOTIN, VERUBULIN, VINBLASTINE SULFATE, VINORELBINE, DESFLURANE, DAVUNETIDE, BELANTAMAB MAFODOTIN, FOSBRETABULIN, ABT-751, MIRVETUXIMAB SORAVTANSINE, IXABEPILONE, POLATUZUMAB VEDOTIN, T-900607, PLITIDEPSIN, APRUTUMAB IXADOTIN, PLINABULIN, TISOTUMAB VEDOTIN, DOLASTATIN-10, FOSBRETABULIN TROMETHAMINE, SAR-408701, CABAZITAXEL, PACLITAXEL DOCOSAHEXAENOIC ACID, ISOFLURANE, ERIBULIN, BMS-275183, INDUSATUMAB VEDOTIN, GLEMBATUMUMAB VEDOTIN, COLCHICINE, VANDORTUZUMAB VEDOTIN, VINBLASTINE, BRENTUXIMAB VEDOTIN, SEVOFLURANE, EPOTHILONE D, SOFITUZUMAB VEDOTIN, INDIBULIN, AZINTUXIZUMAB VEDOTIN, DOXAPRAM, DOXAPRAM HYDROCHLORIDE, LAROTAXEL, RG-7841, GSK-690693, LORVOTUZUMAB MERTANSINE |
| CMF-38042 | PTEN | down-regulates | hsa-mir-615 | represses | R-597 | 1 | 1 | Drugs (65) Regulator Drugs (0)Regulon Drugs (65)ERIBULIN MESYLATE, SAGOPILONE, AGS-16C3F, TELISOTUZUMAB VEDOTIN, DOCETAXEL, FOSBRETABULIN DISODIUM, VINCRISTINE, VINFLUNINE, LEXIBULIN, VINCRISTINE SULFATE, TRASTUZUMAB EMTANSINE, ENFORTUMAB VEDOTIN, VINORELBINE TARTRATE, LIFASTUZUMAB VEDOTIN, KOS-1584, PRALUZATAMAB RAVTANSINE, LADIRATUZUMAB VEDOTIN, PACLITAXEL, CROLIBULIN, PACLITAXEL POLIGLUMEX, PATUPILONE, ASG-5ME, ANG1005, PINATUZUMAB VEDOTIN, VERUBULIN, VINBLASTINE SULFATE, VINORELBINE, DESFLURANE, DAVUNETIDE, BELANTAMAB MAFODOTIN, FOSBRETABULIN, ABT-751, MIRVETUXIMAB SORAVTANSINE, IXABEPILONE, POLATUZUMAB VEDOTIN, T-900607, PLITIDEPSIN, APRUTUMAB IXADOTIN, PLINABULIN, TISOTUMAB VEDOTIN, DOLASTATIN-10, FOSBRETABULIN TROMETHAMINE, SAR-408701, CABAZITAXEL, PACLITAXEL DOCOSAHEXAENOIC ACID, ISOFLURANE, ERIBULIN, BMS-275183, INDUSATUMAB VEDOTIN, GLEMBATUMUMAB VEDOTIN, COLCHICINE, VANDORTUZUMAB VEDOTIN, VINBLASTINE, BRENTUXIMAB VEDOTIN, SEVOFLURANE, EPOTHILONE D, SOFITUZUMAB VEDOTIN, INDIBULIN, AZINTUXIZUMAB VEDOTIN, DOXAPRAM, DOXAPRAM HYDROCHLORIDE, LAROTAXEL, RG-7841, GSK-690693, LORVOTUZUMAB MERTANSINE |