| CMF-17281 | SYNJ2 | down-regulates | POU3F3 | represses | R-2623 | 19 | 2 | Drugs (92) Regulator Drugs (0)Regulon Drugs (92)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ICATIBANT ACETATE, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, LABRADIMIL, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, FASITIBANT, POLMACOXIB, ICATIBANT, ZILTIVEKIMAB |
| CMF-17284 | SYNJ2 | down-regulates | LHX1 | represses | R-2963 | 17 | 3 | Drugs (34) Regulator Drugs (0)Regulon Drugs (34)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, BIRINAPANT, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-17285 | SYNJ2 | down-regulates | LHX1 | represses | R-2965 | 17 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-17286 | SYNJ2 | down-regulates | LHX1 | represses | R-2971 | 17 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-17287 | SYNJ2 | down-regulates | POU3F4 | represses | R-3548 | 10 | 1 | Drugs (84) Regulator Drugs (0)Regulon Drugs (84)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, MELOXICAM, BROMFENAC SODIUM, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB |
| CMF-17288 | SYNJ2 | up-regulates | MAF | activates | R-185 | 19 | 5 | Drugs (1) |
| CMF-17289 | SYNJ2 | up-regulates | MAF | activates | R-184 | 19 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-17290 | SYNJ2 | up-regulates | MAF | activates | R-173 | 19 | 5 | Drugs (89) Regulator Drugs (0)Regulon Drugs (89)PF-04691502, FOSTAMATINIB DISODIUM, INFLIXIMAB, UMBRALISIB, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, PARSACLISIB, INTERFERON GAMMA-1B, ONERCEPT, R-343, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, AME-133V, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, R-348, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, CERDULATINIB, DUVELISIB, L19TNFA, EFALIZUMAB, DACTOLISIB, ZANDELISIB, HMPL-523, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, DAPANSUTRILE, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, IDELALISIB, AZD4818, FIMEPINOSTAT, ENTOSPLETINIB, R-333, GUSACITINIB, REMTOLUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, LIFITEGRAST, ACALISIB, MIVAVOTINIB CITRATE, VELIFLAPON, BMS-817399, OCRIPLASMIN, CAL-263, ERITORAN, ADALIMUMAB, MILATUZUMAB, FOSTAMATINIB, LENIOLISIB, PA-799, PLACULUMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, BUPARLISIB, VESENCUMAB, SF-1126, FIBOFLAPON, PANULISIB |
| CMF-17291 | SYNJ2 | up-regulates | MAF | activates | R-178 | 19 | 5 | Drugs (9) |
| CMF-17295 | SYNJ2 | down-regulates | POU2F3 | represses | R-1706 | 16 | 2 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)2X-121 |
| CMF-17296 | SYNJ2 | down-regulates | POU2F3 | represses | R-1707 | 16 | 2 | Drugs (10) |
| CMF-17297 | SYNJ2 | up-regulates | IRF1 | activates | R-112 | 25 | 5 | Drugs (161) Regulator Drugs (0)Regulon Drugs (161)PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, CSL-324, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, ONERCEPT, VOXTALISIB, BMS-986142, HM-71224, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, BIIB-023, APITOLISIB, AME-133V, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, PF-06651600, AMY-101, LIPEGFILGRASTIM, PEGSUNERCEPT, ABIVERTINIB, VRC-01LS, GOLIMUMAB, ABIVERTINIB MALEATE, VICRIVIROC, MEDI-2338, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, CAROTUXIMAB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, EFALIZUMAB, DACTOLISIB, BOSUTINIB, FILGRASTIM, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, RILZABRUTINIB, BALUGRASTIM, AFELIMOMAB, SPEBRUTINIB, OZORALIZUMAB, PILARALISIB, ILORASERTIB, DAPANSUTRILE, CERTOLIZUMAB PEGOL, RO-5458640, TASELISIB, L19SIP 131I, AMG-319, IBRUTINIB, TADEKINIG ALFA, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, ENTOLIMOD, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, ZANUBRUTINIB, XL-228, FIMEPINOSTAT, SATRALIZUMAB, EVOBRUTINIB, CPG-52852, SELGANTOLIMOD, IMIQUIMOD, OTLERTUZUMAB, REMTOLUMAB, BI-836826, MOTOLIMOD, TREGALIZUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, BMS-813160, PF-04634817, TG100-801, INCB-9471, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, VICRIVIROC MALEATE, LENOGRASTIM, POSELTINIB, LIFITEGRAST, VB-201, ACALISIB, PF-232798, ZANOLIMUMAB, GSK-2245035, PIRTOBRUTINIB, TELRATOLIMOD, AZD5672, IBALIZUMAB, OCRIPLASMIN, CAL-263, UB-421, ACALABRUTINIB, ERITORAN, ADALIMUMAB, MILATUZUMAB, VOLOCIXIMAB, TOMARALIMAB, ELSUBRUTINIB, BRANEBRUTINIB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, TIRABRUTINIB, FENEBRUTINIB, LEVILIMAB, GSK-1059615, PEGFILGRASTIM, BUPARLISIB, VESENCUMAB, NARATUXIMAB EMTANSINE, AMG-557, SF-1126, ORELABRUTINIB, GSK-1070806, AL-78898A, ENMD-981693, PANULISIB, NELFINAVIR |
| CMF-17298 | SYNJ2 | up-regulates | IRF1 | activates | R-119 | 25 | 5 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)DIAZOXIDE |
| CMF-17299 | SYNJ2 | up-regulates | IRF1 | activates | R-123 | 25 | 5 | Drugs (1) |
| CMF-17302 | SYNJ2 | down-regulates | FEV | represses | R-3030 | 5 | 3 | Drugs (71) Regulator Drugs (0)Regulon Drugs (71)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, NEDOSIRAN SODIUM, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-17303 | SYNJ2 | down-regulates | FEV | represses | R-3034 | 5 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-17304 | SYNJ2 | down-regulates | FEV | represses | R-3032 | 5 | 3 | Drugs (18) Regulator Drugs (0)Regulon Drugs (18)FOSTAMATINIB DISODIUM, FIBOFLAPON SODIUM, R-343, AME-133V, R-348, CERDULATINIB, EFALIZUMAB, HMPL-523, ENTOSPLETINIB, R-333, GUSACITINIB, LIFITEGRAST, MIVAVOTINIB CITRATE, VELIFLAPON, FOSTAMATINIB, LANRAPLENIB, MIVAVOTINIB, FIBOFLAPON |
| CMF-17305 | SYNJ2 | up-regulates | BCL6 | activates | R-635 | 23 | 1 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-17306 | SYNJ2 | up-regulates | DR1 | activates | R-2981 | 8 | 3 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)DIAZOXIDE |
| CMF-17307 | SYNJ2 | up-regulates | DR1 | activates | R-2987 | 8 | 3 | Drugs (4) |
| CMF-17309 | SYNJ2 | down-regulates | PAX7 | represses | R-3698 | 3 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-17313 | SYNJ2 | up-regulates | STAT5A | activates | R-2945 | 21 | 3 | Drugs (7) |
| CMF-17314 | SYNJ2 | up-regulates | STAT5A | activates | R-2955 | 21 | 3 | Drugs (1) |
| CMF-17315 | SYNJ2 | down-regulates | ZBTB7B | represses | R-2800 | 2 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-17316 | SYNJ2 | up-regulates | ZIC1 | activates | R-3437 | 8 | 3 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)DIAZOXIDE |
| CMF-17317 | SYNJ2 | up-regulates | ZIC1 | activates | R-3436 | 8 | 3 | Drugs (1) |
| CMF-17321 | SYNJ2 | down-regulates | LHX5 | represses | R-3052 | 11 | 1 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-17327 | SYNJ2 | down-regulates | HOXC8 | represses | R-2231 | 2 | 1 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ASK-8007 |
| CMF-17331 | SYNJ2 | up-regulates | REL | activates | R-246 | 8 | 2 | Drugs (63) Regulator Drugs (0)Regulon Drugs (63)PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, DS-7423, GSK-2269557, INCB-40093, PAXALISIB, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, DUVELISIB, DACTOLISIB, ZANDELISIB, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, CERTOLIZUMAB PEGOL, TASELISIB, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, FIMEPINOSTAT, REMTOLUMAB, DUPILUMAB, ACALISIB, CAL-263, ADALIMUMAB, VOLOCIXIMAB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB |
| CMF-17335 | SYNJ2 | up-regulates | MSX1 | activates | R-2821 | 12 | 2 | Drugs (1) |
| CMF-38852 | SYNJ2 | down-regulates | hsa-mir-197 | represses | R-1510 | 3 | 1 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |