Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
SRPX2 - sushi repeat containing protein X-linked 2
Function
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 27286 | ENSG00000102359 | SRPX2 | O60687 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1068 | Pr-0 | 1 | 1 | 4 |
| R-1100 | Pr-0 | 1 | 1 | 8 |
| R-1300 | Pr-0 | 1 | 1 | 25 |
| R-1356 | Pr-0 | 1 | 1 | 4 |
| R-138 | Pr-0 | 1 | 1 | 7 |
| R-142 | Pr-6 | 1 | 1 | 8 |
| R-1487 | Pr-6 | 1 | 1 | 11 |
| R-1676 | Pr-0 | 1 | 1 | 13 |
| R-1681 | Pr-6 | 1 | 1 | 12 |
| R-175 | Pr-0 | 1 | 1 | 11 |
| R-1834 | Pr-6 | 1 | 1 | 8 |
| R-1904 | Pr-0 | 1 | 1 | 9 |
| R-1911 | Pr-6 | 1 | 1 | 6 |
| R-1925 | Pr-0 | 1 | 1 | 1 |
| R-1936 | Pr-6 | 1 | 1 | 14 |
| R-1982 | Pr-137 | 1 | 1 | 14 |
| R-1985 | Pr-6 | 1 | 1 | 23 |
| R-2056 | Pr-6 | 1 | 1 | 12 |
| R-209 | Pr-0 | 1 | 1 | 6 |
| R-2100 | Pr-0 | 1 | 1 | 12 |
| R-217 | Pr-6 | 1 | 1 | 11 |
| R-2195 | Pr-6 | 1 | 1 | 12 |
| R-2452 | Pr-0 | 1 | 1 | 3 |
| R-258 | Pr-0 | 1 | 1 | 9 |
| R-2589 | Pr-0 | 1 | 1 | 4 |
| R-2687 | Pr-0 | 1 | 1 | 14 |
| R-2746 | Pr-0 | 1 | 1 | 17 |
| R-2752 | Pr-6 | 1 | 1 | 13 |
| R-276 | Pr-0 | 1 | 1 | 13 |
| R-2863 | Pr-0 | 1 | 1 | 2 |
| R-3039 | Pr-0 | 1 | 1 | 6 |
| R-3103 | Pr-0 | 1 | 1 | 9 |
| R-3127 | Pr-0 | 1 | 1 | 7 |
| R-3133 | Pr-0 | 1 | 1 | 8 |
| R-3152 | Pr-0 | 1 | 1 | 2 |
| R-3161 | Pr-0 | 1 | 1 | 13 |
| R-3166 | Pr-6 | 1 | 1 | 11 |
| R-3173 | Pr-133 | 1 | 1 | 18 |
| R-3174 | Pr-6 | 1 | 1 | 17 |
| R-357 | Pr-0 | 1 | 1 | 8 |
| R-375 | Pr-0 | 1 | 1 | 9 |
| R-379 | Pr-6 | 1 | 1 | 10 |
| R-445 | Pr-0 | 1 | 1 | 15 |
| R-450 | Pr-6 | 1 | 1 | 11 |
| R-629 | Pr-6 | 1 | 1 | 10 |
| R-648 | Pr-0 | 1 | 1 | 7 |
| R-704 | Pr-6 | 1 | 1 | 7 |
| R-848 | Pr-0 | 1 | 1 | 9 |
| R-99 | Pr-0 | 1 | 1 | 13 |