Program – gbmMINER Portal

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Program – gbmMINER Portal

Program

Program Pr-53

Genes (36)

STRN4, MAP3K1, SLC25A15, ITM2B, RB1, GPHN, HMGB1, PCDHGC3, ZNF85, ZNF175, ZNF230, ZNF222, ZNF606, ZNF134, MTHFD1, PSMD3, PSMF1, PROSC, FIBP, PRKD1, KRIT1, FUBP3, GOSR2, C11orf57, SP3, ZKSCAN5, ZNF20, ZNF254, PPP5C, MTMR3, FOXRED2, NCBP2, PSME3, ABHD2, PGGT1B, KCNIP1

Regulons (11)

R-592, R-941, R-1153, R-1262, R-2153, R-2520, R-2527, R-3099, R-3288, R-3596, R-3624

Regulons in program Pr-53

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-592	-0.686288	9	2
R-941	-0.517315	5	13
R-1153	-0.645085	6	24
R-1262	-0.685264	6	10
R-2153	0.948914	6	2
R-2520	-0.99058	5	5
R-2527	-0.583337	5	6
R-3099	-1.03001	8	11
R-3288	0.90042	10	9
R-3596	-0.430633	5	1
R-3624	-0.517315	5	1

Genes in program Pr-53

EnsEMBL Id	Entrez Id	Preferred
ENSG00000090372	29888	STRN4
ENSG00000095015	4214	MAP3K1
ENSG00000102743	10166	SLC25A15
ENSG00000136156	9445	ITM2B
ENSG00000139687	5925	RB1
ENSG00000171723	10243	GPHN
ENSG00000189403	3146	HMGB1
ENSG00000240184	5098	PCDHGC3
ENSG00000278091	7639	ZNF85
ENSG00000105497	7728	ZNF175
ENSG00000159882	7773	ZNF230
ENSG00000159885	7673	ZNF222
ENSG00000166704	80095	ZNF606
ENSG00000213762	7693	ZNF134
ENSG00000100714	4522	MTHFD1
ENSG00000108344	5709	PSMD3
ENSG00000125818	9491	PSMF1
ENSG00000147471	11212	PROSC
ENSG00000172500	9158	FIBP
ENSG00000184304	5587	PRKD1
ENSG00000001631	889	KRIT1
ENSG00000107164	8939	FUBP3
ENSG00000108433	9570	GOSR2
ENSG00000150776	55216	C11orf57
ENSG00000172845	6670	SP3
ENSG00000196652	23660	ZKSCAN5
ENSG00000132010	7568	ZNF20
ENSG00000213096	9534	ZNF254
ENSG00000011485	5536	PPP5C
ENSG00000100330	8897	MTMR3
ENSG00000100350	80020	FOXRED2
ENSG00000114503	22916	NCBP2
ENSG00000131467	10197	PSME3
ENSG00000140526	11057	ABHD2
ENSG00000164219	5229	PGGT1B
ENSG00000182132	30820	KCNIP1

Causal Mechanistic Flows with Program Pr-53

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs

CMFlow summary not available

Enrichment summary not available