| CMF-24281 | SMCHD1 | up-regulates | ZBTB16 | activates | R-2185 | 16 | 3 | Drugs (4) |
| CMF-24284 | SMCHD1 | up-regulates | RXRA | activates | R-3213 | 13 | 1 | Drugs (12) Regulator Drugs (2)SDX-101, DANTHRON Regulon Drugs (10)SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, BHQ-880, ABITUZUMAB |
| CMF-24287 | SMCHD1 | down-regulates | LHX1 | represses | R-2965 | 17 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24288 | SMCHD1 | down-regulates | LHX1 | represses | R-2972 | 17 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24291 | SMCHD1 | down-regulates | FOXL1 | represses | R-1848 | 25 | 4 | Drugs (110) Regulator Drugs (0)Regulon Drugs (110)CISATRACURIUM, PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, GSK-1995057, RUPATADINE, DOXYLAMINE SUCCINATE, CISATRACURIUM BESYLATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, SUXAMETHONIUM, PRAMLINTIDE, CYPROHEPTADINE HYDROCHLORIDE, BRINZOLAMIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, MIVACURIUM, EBASTINE, SULTHIAME, CINNARIZINE, HYDROXYZINE, LORATADINE, DORZOLAMIDE, LY2624803, ROCURONIUM BROMIDE, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, METHAZOLAMIDE, MIVACURIUM CHLORIDE, PRAMLINTIDE ACETATE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, TOPIRAMATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, POLMACOXIB, ROCURONIUM, CETIRIZINE, METHDILAZINE, DAVALINTIDE |
| CMF-24294 | SMCHD1 | up-regulates | FOXO1 | activates | R-709 | 21 | 5 | Drugs (1) |
| CMF-24297 | SMCHD1 | up-regulates | FOXO1 | activates | R-710 | 21 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24304 | SMCHD1 | up-regulates | MAFB | activates | R-1902 | 25 | 6 | Drugs (29) Regulator Drugs (0)Regulon Drugs (29)FOSTAMATINIB DISODIUM, FIBOFLAPON SODIUM, HYDROXYCHLOROQUINE, R-343, AME-133V, R-348, CERDULATINIB, VESATOLIMOD, AZD-8848, EFALIZUMAB, HMPL-523, HYDROXYCHLOROQUINE SULFATE, PETESICATIB, ENTOSPLETINIB, CPG-52852, R-333, IMIQUIMOD, IC14, GUSACITINIB, LIFITEGRAST, VB-201, GSK-2245035, MIVAVOTINIB CITRATE, VELIFLAPON, TELRATOLIMOD, FOSTAMATINIB, LANRAPLENIB, MIVAVOTINIB, FIBOFLAPON |
| CMF-24305 | SMCHD1 | up-regulates | MAFB | activates | R-1914 | 25 | 6 | Drugs (1) |
| CMF-24306 | SMCHD1 | up-regulates | MAFB | activates | R-1906 | 25 | 6 | Drugs (9) |
| CMF-24307 | SMCHD1 | up-regulates | MAFB | activates | R-1909 | 25 | 6 | Drugs (10) |
| CMF-24309 | SMCHD1 | up-regulates | MAFB | activates | R-1916 | 25 | 6 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-24310 | SMCHD1 | up-regulates | SREBF1 | activates | R-2497 | 12 | 3 | Drugs (7) |
| CMF-24311 | SMCHD1 | up-regulates | SREBF1 | activates | R-2503 | 12 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24312 | SMCHD1 | up-regulates | SREBF1 | activates | R-2500 | 12 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24313 | SMCHD1 | up-regulates | MAF | activates | R-185 | 19 | 5 | Drugs (1) |
| CMF-24314 | SMCHD1 | up-regulates | MAF | activates | R-184 | 19 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24315 | SMCHD1 | up-regulates | MAF | activates | R-173 | 19 | 5 | Drugs (89) Regulator Drugs (0)Regulon Drugs (89)PF-04691502, FOSTAMATINIB DISODIUM, INFLIXIMAB, UMBRALISIB, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, PARSACLISIB, INTERFERON GAMMA-1B, ONERCEPT, R-343, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, AME-133V, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, R-348, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, CERDULATINIB, DUVELISIB, L19TNFA, EFALIZUMAB, DACTOLISIB, ZANDELISIB, HMPL-523, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, DAPANSUTRILE, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, IDELALISIB, AZD4818, FIMEPINOSTAT, ENTOSPLETINIB, R-333, GUSACITINIB, REMTOLUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, LIFITEGRAST, ACALISIB, MIVAVOTINIB CITRATE, VELIFLAPON, BMS-817399, OCRIPLASMIN, CAL-263, ERITORAN, ADALIMUMAB, MILATUZUMAB, FOSTAMATINIB, LENIOLISIB, PA-799, PLACULUMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, BUPARLISIB, VESENCUMAB, SF-1126, FIBOFLAPON, PANULISIB |
| CMF-24319 | SMCHD1 | down-regulates | PAX1 | represses | R-254 | 3 | 2 | Drugs (29) Regulator Drugs (0)Regulon Drugs (29)RUPATADINE, CSL-324, DASATINIB, LIPEGFILGRASTIM, MEDI-2338, CAROTUXIMAB, BOSUTINIB, BAFETINIB, FILGRASTIM, BALUGRASTIM, ILORASERTIB, JNJ-26483327, TADEKINIG ALFA, PETESICATIB, NEIHULIZUMAB, XL-228, OTLERTUZUMAB, BI-836826, TOLIMIDONE, ERITORAN TETRASODIUM, TG100-801, LENOGRASTIM, OCRIPLASMIN, ERITORAN, PEGFILGRASTIM, NARATUXIMAB EMTANSINE, AMG-557, GSK-1070806, ENMD-981693 |
| CMF-24321 | SMCHD1 | down-regulates | ALX4 | represses | R-2922 | 20 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24324 | SMCHD1 | down-regulates | SOX1 | represses | R-1831 | 20 | 4 | Drugs (2) |
| CMF-24326 | SMCHD1 | down-regulates | FEV | represses | R-3034 | 5 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24327 | SMCHD1 | down-regulates | FEV | represses | R-3032 | 5 | 2 | Drugs (18) Regulator Drugs (0)Regulon Drugs (18)FOSTAMATINIB DISODIUM, FIBOFLAPON SODIUM, R-343, AME-133V, R-348, CERDULATINIB, EFALIZUMAB, HMPL-523, ENTOSPLETINIB, R-333, GUSACITINIB, LIFITEGRAST, MIVAVOTINIB CITRATE, VELIFLAPON, FOSTAMATINIB, LANRAPLENIB, MIVAVOTINIB, FIBOFLAPON |
| CMF-24329 | SMCHD1 | up-regulates | BCL6 | activates | R-635 | 23 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-24331 | SMCHD1 | down-regulates | POU3F1 | represses | R-1649 | 25 | 4 | Drugs (4) |
| CMF-24336 | SMCHD1 | down-regulates | EMX1 | represses | R-3048 | 14 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24340 | SMCHD1 | up-regulates | IRF3 | activates | R-2429 | 25 | 4 | Drugs (12) Regulator Drugs (0)Regulon Drugs (12)OPROZOMIB, INTERFERON GAMMA-1B, IXAZOMIB, MARIZOMIB, NIVOCASAN, BORTEZOMIB, EMRICASAN, EMAPUNIL, BELNACASAN, IXAZOMIB CITRATE, ONO-2952, CARFILZOMIB |
| CMF-24342 | SMCHD1 | up-regulates | IRF3 | activates | R-2441 | 25 | 4 | Drugs (2) |
| CMF-24343 | SMCHD1 | up-regulates | IRF3 | activates | R-2430 | 25 | 4 | Drugs (6) |
| CMF-24345 | SMCHD1 | down-regulates | FOXD2 | represses | R-2583 | 6 | 2 | Drugs (1) |
| CMF-24350 | SMCHD1 | up-regulates | NR1H2 | activates | R-3606 | 4 | 1 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ANG1005 |
| CMF-24351 | SMCHD1 | down-regulates | MNX1 | represses | R-2262 | 4 | 2 | Drugs (59) Regulator Drugs (0)Regulon Drugs (59)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN |
| CMF-24356 | SMCHD1 | up-regulates | MAX | activates | R-3491 | 18 | 1 | Drugs (4) |
| CMF-24357 | SMCHD1 | up-regulates | CEBPB | activates | R-1305 | 23 | 6 | Drugs (5) |
| CMF-24361 | SMCHD1 | up-regulates | CEBPB | activates | R-1314 | 23 | 6 | Drugs (1) |
| CMF-24366 | SMCHD1 | up-regulates | MSX1 | activates | R-2817 | 12 | 6 | Drugs (10) |
| CMF-24368 | SMCHD1 | up-regulates | MSX1 | activates | R-2821 | 12 | 6 | Drugs (1) |
| CMF-24369 | SMCHD1 | up-regulates | MSX1 | activates | R-2824 | 12 | 6 | Drugs (2) |
| CMF-24375 | SMCHD1 | down-regulates | TBX1 | represses | R-2241 | 9 | 1 | Drugs (2) |