Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
PLAUR - plasminogen activator, urokinase receptor
Function
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 5329 | ENSG00000011422 | PLAUR | Q03405 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-112 | Pr-7 | 1 | 1 | 20 |
| R-117 | Pr-4 | 1 | 1 | 99 |
| R-1358 | Pr-4 | 1 | 1 | 6 |
| R-137 | Pr-7 | 1 | 1 | 22 |
| R-157 | Pr-28 | 1 | 1 | 19 |
| R-158 | Pr-7 | 1 | 1 | 59 |
| R-1592 | Pr-4 | 1 | 1 | 87 |
| R-1608 | Pr-4 | 1 | 1 | 8 |
| R-1679 | Pr-4 | 1 | 1 | 92 |
| R-173 | Pr-7 | 1 | 1 | 34 |
| R-174 | Pr-4 | 1 | 1 | 9 |
| R-1829 | Pr-4 | 1 | 1 | 83 |
| R-1895 | Pr-28 | 1 | 1 | 7 |
| R-1926 | Pr-4 | 1 | 1 | 75 |
| R-203 | Pr-7 | 1 | 1 | 9 |
| R-207 | Pr-7 | 1 | 1 | 44 |
| R-2123 | Pr-4 | 1 | 1 | 85 |
| R-2161 | Pr-4 | 1 | 1 | 71 |
| R-2305 | Pr-4 | 1 | 1 | 12 |
| R-2331 | Pr-28 | 1 | 1 | 6 |
| R-257 | Pr-7 | 1 | 1 | 56 |
| R-2585 | Pr-4 | 1 | 1 | 82 |
| R-259 | Pr-4 | 1 | 1 | 17 |
| R-2601 | Pr-28 | 1 | 1 | 13 |
| R-2765 | Pr-28 | 1 | 1 | 15 |
| R-2885 | Pr-4 | 1 | 1 | 81 |
| R-2943 | Pr-4 | 1 | 1 | 14 |
| R-3029 | Pr-28 | 1 | 1 | 20 |
| R-3126 | Pr-4 | 1 | 1 | 11 |
| R-3131 | Pr-28 | 1 | 1 | 11 |
| R-3134 | Pr-4 | 1 | 1 | 97 |
| R-3345 | Pr-4 | 1 | 1 | 2 |
| R-3348 | Pr-4 | 1 | 1 | 104 |
| R-3364 | Pr-4 | 1 | 1 | 5 |
| R-3377 | Pr-4 | 1 | 1 | 7 |
| R-3571 | Pr-28 | 1 | 1 | 9 |
| R-370 | Pr-7 | 1 | 1 | 30 |
| R-371 | Pr-4 | 1 | 1 | 74 |
| R-413 | Pr-7 | 1 | 1 | 23 |
| R-419 | Pr-4 | 1 | 1 | 90 |
| R-93 | Pr-7 | 1 | 1 | 17 |