Gene details
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
OLFML3 - olfactomedin like 3
Function
Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 56944 | ENSG00000116774 | OLFML3 | Q9NRN5 |
Gene Regulons
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-112 | Pr-7 | 1 | 1 | 20 |
| R-1284 | Pr-5 | 1 | 1 | 7 |
| R-137 | Pr-7 | 1 | 1 | 22 |
| R-158 | Pr-7 | 1 | 1 | 59 |
| R-173 | Pr-7 | 1 | 1 | 34 |
| R-178 | Pr-5 | 1 | 1 | 6 |
| R-1907 | Pr-5 | 1 | 1 | 13 |
| R-192 | Pr-7 | 1 | 1 | 74 |
| R-1984 | Pr-21 | 1 | 1 | 8 |
| R-207 | Pr-7 | 1 | 1 | 44 |
| R-213 | Pr-5 | 1 | 1 | 8 |
| R-232 | Pr-7 | 1 | 1 | 77 |
| R-2590 | Pr-5 | 1 | 1 | 6 |
| R-2623 | Pr-5 | 1 | 1 | 8 |
| R-2688 | Pr-5 | 1 | 1 | 16 |
| R-275 | Pr-7 | 1 | 1 | 66 |
| R-290 | Pr-7 | 1 | 1 | 68 |
| R-2961 | Pr-5 | 1 | 1 | 16 |
| R-3105 | Pr-5 | 1 | 1 | 7 |
| R-315 | Pr-7 | 1 | 1 | 25 |
| R-3548 | Pr-5 | 1 | 1 | 6 |
| R-356 | Pr-7 | 1 | 1 | 57 |
| R-370 | Pr-7 | 1 | 1 | 30 |
| R-376 | Pr-5 | 1 | 1 | 15 |
| R-395 | Pr-7 | 1 | 1 | 44 |
| R-413 | Pr-7 | 1 | 1 | 23 |
| R-438 | Pr-7 | 1 | 1 | 44 |
| R-86 | Pr-7 | 1 | 1 | 62 |
| R-93 | Pr-7 | 1 | 1 | 17 |
| R-97 | Pr-7 | 1 | 1 | 44 |