| CMF-06762 | ATRX | down-regulates | LEF1 | activates | R-1418 | 18 | 12 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-14359 | SIPA1L1 | up-regulates | STAT5B | activates | R-1544 | 9 | 1 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-16572 | RBM19 | down-regulates | STAT5B | activates | R-1544 | 9 | 4 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-22067 | SSTR4 | up-regulates | LEF1 | activates | R-1418 | 18 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-22386 | IDH1 | down-regulates | LEF1 | activates | R-1418 | 18 | 13 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-25461 | PCDHGB3 | up-regulates | STAT5B | activates | R-1544 | 9 | 4 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-29108 | FOLH1B | down-regulates | LEF1 | activates | R-1418 | 18 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-31331 | CLASS_I_PI3K_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-31382 | ANGIOPOIETIN_RECEPTOR_TIE2_MEDIATED_SIGNALING | up-regulates | STAT5B | activates | R-1544 | 9 | 3 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-31420 | IL3_MEDIATED_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 3 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-31679 | PDGFR_BETA_SIGNALING_PATHWAY | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-31740 | PAR1_MEDIATED_THROMBIN_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 3 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-31795 | ERBB4_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 4 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-31818 | SIGNALING_EVENTS_MEDIATED_BY_VEGFR1_AND_VEGFR2 | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-31997 | E_CADHERIN_SIGNALING_NASCENT_ADHERENS_JUNCTION | up-regulates | STAT5B | activates | R-1544 | 9 | 3 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-32053 | SIGNALING_EVENTS_MEDIATED_BY_HEPATOCYTE_GFR | up-regulates | STAT5B | activates | R-1544 | 9 | 3 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-32178 | VEGFR3_SIGNALING_IN_LYMPHATIC_ENDOTHELIUM | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-32471 | IL4_MEDIATED_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 1 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-32518 | CXCR4_MEDIATED_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-32600 | IL23_MEDIATED_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 3 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-32704 | NONGENOTROPIC_ANDROGEN_SIGNALING | up-regulates | STAT5B | activates | R-1544 | 9 | 3 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33094 | GMCSF_MEDIATED_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33120 | IL5_MEDIATED_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 3 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33204 | FC_EPSILON_RECEPTOR_I_SIGNALING_IN_MAST_CELLS | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33245 | EPHRIN_B_REVERSE_SIGNALING | up-regulates | STAT5B | activates | R-1544 | 9 | 4 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33278 | IL2_SIGNALING_EVENTS_MEDIATED_BY_PI3K | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33404 | TCR_SIGNALING_IN_NAIVE_CD4+_T_CELLS | up-regulates | LEF1 | activates | R-1418 | 18 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-33503 | NEPHRIN_NEPH1_SIGNALING_IN_THE_KIDNEY_PODOCYTE | up-regulates | STAT5B | activates | R-1544 | 9 | 4 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33609 | ERBB2_ERBB3_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33618 | PLASMA_MEMBRANE_ESTROGEN_RECEPTOR_SIGNALING | up-regulates | STAT5B | activates | R-1544 | 9 | 1 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33689 | BCR_SIGNALING_PATHWAY | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33731 | IL6_MEDIATED_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33766 | FGF_SIGNALING_PATHWAY | up-regulates | STAT5B | activates | R-1544 | 9 | 3 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33836 | N_CADHERIN_SIGNALING_EVENTS | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |
| CMF-33845 | P75_MEDIATED_SIGNALING | up-regulates | STAT5B | activates | R-1544 | 9 | 2 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)BINTRAFUSP ALFA, TRILACICLIB, RIBOCICLIB, PALBOCICLIB, ABEMACICLIB, PHA-793887, LUSPATERCEPT, AZD-5438, RIBOCICLIB SUCCINATE, TRILACICLIB DIHYDROCHLORIDE, UCN-01, ALVOCIDIB, FRESOLIMUMAB, RONICICLIB, AT-7519, MARIMASTAT |