Regulator

Summary of regulator annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

hsa-mir-488 -

Function

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
-		hsa-mir-488

List of causal flows containing the regulator.

Causal Flows are statistically significant links between putative causal events (somatic mutations, copy number variations, chromosomal translocations, etc.) and the activity levels of regulators and regulons. In the causal flow, a mutation may causally activate or deactivate a downstream regulator which then might up- down-regulates a regulonthat contains genes with similar expression profiles and binding sites.

Causal Mechanistic Flows with hsa-mir-488 as Regulator

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-34180	ANO1	up-regulates	hsa-mir-488	represses	R-2767	19	1	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-34833	ITPR3	down-regulates	hsa-mir-488	represses	R-2016	19	1	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34871	MX2	down-regulates	hsa-mir-488	represses	R-2402	19	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-34872	MX2	down-regulates	hsa-mir-488	represses	R-2837	19	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-34873	MX2	down-regulates	hsa-mir-488	represses	R-3143	19	3	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, TOSEDOSTAT, RIBAVIRIN
CMF-34912	POTEE	up-regulates	hsa-mir-488	represses	R-3143	19	1	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, TOSEDOSTAT, RIBAVIRIN
CMF-35946	OR4N4	down-regulates	hsa-mir-488	represses	R-3143	19	1	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, TOSEDOSTAT, RIBAVIRIN
CMF-36371	DIAPH2	up-regulates	hsa-mir-488	represses	R-246	19	3	Drugs (63) Regulator Drugs (0) Regulon Drugs (63) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, DS-7423, GSK-2269557, INCB-40093, PAXALISIB, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, DUVELISIB, DACTOLISIB, ZANDELISIB, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, CERTOLIZUMAB PEGOL, TASELISIB, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, FIMEPINOSTAT, REMTOLUMAB, DUPILUMAB, ACALISIB, CAL-263, ADALIMUMAB, VOLOCIXIMAB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB
CMF-36372	DIAPH2	up-regulates	hsa-mir-488	represses	R-290	19	3	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-36373	DIAPH2	up-regulates	hsa-mir-488	represses	R-2016	19	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-36965	BMP5	up-regulates	hsa-mir-488	represses	R-259	19	2	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-36966	BMP5	up-regulates	hsa-mir-488	represses	R-3370	19	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-37645	FMN1	down-regulates	hsa-mir-488	represses	R-2402	19	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37742	ZNF516	down-regulates	hsa-mir-488	represses	R-2224	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37743	ZNF516	down-regulates	hsa-mir-488	represses	R-2402	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37744	ZNF516	down-regulates	hsa-mir-488	represses	R-2446	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37745	ZNF516	down-regulates	hsa-mir-488	represses	R-2837	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37746	ZNF516	down-regulates	hsa-mir-488	represses	R-1459	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37747	ZNF516	down-regulates	hsa-mir-488	represses	R-1820	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37804	ANKRD33	down-regulates	hsa-mir-488	represses	R-259	19	6	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-37805	ANKRD33	down-regulates	hsa-mir-488	represses	R-2767	19	6	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-37806	ANKRD33	down-regulates	hsa-mir-488	represses	R-3348	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-37807	ANKRD33	down-regulates	hsa-mir-488	represses	R-3370	19	6	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-37808	ANKRD33	down-regulates	hsa-mir-488	represses	R-1358	19	6	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-37809	ANKRD33	down-regulates	hsa-mir-488	represses	R-1829	19	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-37983	SDHAP3	down-regulates	hsa-mir-488	represses	R-2224	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37984	SDHAP3	down-regulates	hsa-mir-488	represses	R-2446	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37985	SDHAP3	down-regulates	hsa-mir-488	represses	R-2837	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37986	SDHAP3	down-regulates	hsa-mir-488	represses	R-1459	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37987	SDHAP3	down-regulates	hsa-mir-488	represses	R-1820	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-37988	SDHAP3	down-regulates	hsa-mir-488	represses	R-2016	19	6	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-38037	PTEN	down-regulates	hsa-mir-488	represses	R-2402	19	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-38805	CDH18	down-regulates	hsa-mir-488	represses	R-2224	19	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-38806	CDH18	down-regulates	hsa-mir-488	represses	R-246	19	5	Drugs (63) Regulator Drugs (0) Regulon Drugs (63) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, DS-7423, GSK-2269557, INCB-40093, PAXALISIB, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, DUVELISIB, DACTOLISIB, ZANDELISIB, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, CERTOLIZUMAB PEGOL, TASELISIB, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, FIMEPINOSTAT, REMTOLUMAB, DUPILUMAB, ACALISIB, CAL-263, ADALIMUMAB, VOLOCIXIMAB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB
CMF-38807	CDH18	down-regulates	hsa-mir-488	represses	R-2402	19	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-38808	CDH18	down-regulates	hsa-mir-488	represses	R-2446	19	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-38809	CDH18	down-regulates	hsa-mir-488	represses	R-2837	19	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-38890	CNTNAP3	down-regulates	hsa-mir-488	represses	R-246	19	2	Drugs (63) Regulator Drugs (0) Regulon Drugs (63) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, DS-7423, GSK-2269557, INCB-40093, PAXALISIB, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, DUVELISIB, DACTOLISIB, ZANDELISIB, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, CERTOLIZUMAB PEGOL, TASELISIB, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, FIMEPINOSTAT, REMTOLUMAB, DUPILUMAB, ACALISIB, CAL-263, ADALIMUMAB, VOLOCIXIMAB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB
CMF-38891	CNTNAP3	down-regulates	hsa-mir-488	represses	R-3370	19	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-39281	SLFN13	down-regulates	hsa-mir-488	represses	R-158	19	6	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, UMBRALISIB, FIBOFLAPON SODIUM, ATN-161, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, VICRIVIROC, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, PILARALISIB, ILORASERTIB, PREXIGEBERSEN, TASELISIB, L19SIP 131I, AMG-319, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, CAFFEINE, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, ADENOSINE, VB-201, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, MILATUZUMAB, VOLOCIXIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, LINTUZUMAB, LEVILIMAB, GSK-1059615, BUPARLISIB, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, FIBOFLAPON, ENMD-981693, PANULISIB, NELFINAVIR
CMF-39282	SLFN13	down-regulates	hsa-mir-488	represses	R-246	19	6	Drugs (63) Regulator Drugs (0) Regulon Drugs (63) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, DS-7423, GSK-2269557, INCB-40093, PAXALISIB, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, DUVELISIB, DACTOLISIB, ZANDELISIB, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, CERTOLIZUMAB PEGOL, TASELISIB, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, FIMEPINOSTAT, REMTOLUMAB, DUPILUMAB, ACALISIB, CAL-263, ADALIMUMAB, VOLOCIXIMAB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB
CMF-39283	SLFN13	down-regulates	hsa-mir-488	represses	R-290	19	6	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-39284	SLFN13	down-regulates	hsa-mir-488	represses	R-2402	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-39285	SLFN13	down-regulates	hsa-mir-488	represses	R-2446	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-39286	SLFN13	down-regulates	hsa-mir-488	represses	R-2837	19	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-39319	INPP5J	up-regulates	hsa-mir-488	represses	R-158	19	10	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, UMBRALISIB, FIBOFLAPON SODIUM, ATN-161, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, VICRIVIROC, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, PILARALISIB, ILORASERTIB, PREXIGEBERSEN, TASELISIB, L19SIP 131I, AMG-319, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, CAFFEINE, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, ADENOSINE, VB-201, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, MILATUZUMAB, VOLOCIXIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, LINTUZUMAB, LEVILIMAB, GSK-1059615, BUPARLISIB, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, FIBOFLAPON, ENMD-981693, PANULISIB, NELFINAVIR
CMF-39320	INPP5J	up-regulates	hsa-mir-488	represses	R-246	19	10	Drugs (63) Regulator Drugs (0) Regulon Drugs (63) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, DS-7423, GSK-2269557, INCB-40093, PAXALISIB, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, DUVELISIB, DACTOLISIB, ZANDELISIB, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, CERTOLIZUMAB PEGOL, TASELISIB, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, FIMEPINOSTAT, REMTOLUMAB, DUPILUMAB, ACALISIB, CAL-263, ADALIMUMAB, VOLOCIXIMAB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB
CMF-39321	INPP5J	up-regulates	hsa-mir-488	represses	R-257	19	10	Drugs (149) Regulator Drugs (0) Regulon Drugs (149) PF-04691502, FOSTAMATINIB DISODIUM, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, ONERCEPT, R-343, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, ABATACEPT, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, R-348, AMY-101, PEGSUNERCEPT, GOLIMUMAB, VICRIVIROC, CAFFEINE, CITRATED, MEDI-2338, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, CERDULATINIB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, BOSUTINIB, BAFETINIB, ZANDELISIB, HMPL-523, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, TASELISIB, JNJ-26483327, L19SIP 131I, AMG-319, UCN-01, TADEKINIG ALFA, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, FIMEPINOSTAT, ENTOSPLETINIB, SATRALIZUMAB, CPG-52852, SELGANTOLIMOD, R-333, IMIQUIMOD, GUSACITINIB, REMTOLUMAB, TOLIMIDONE, CAFFEINE, MOTOLIMOD, TOMIVOSERTIB, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, PEGCETACOPLAN, VICRIVIROC MALEATE, ADENOSINE, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, MIVAVOTINIB CITRATE, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, MILATUZUMAB, FOSTAMATINIB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, LINTUZUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, BUPARLISIB, VESENCUMAB, GSK-690693, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, GSK-1070806, FIBOFLAPON, AL-78898A, ENMD-981693, PANULISIB
CMF-39322	INPP5J	up-regulates	hsa-mir-488	represses	R-290	19	10	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-39323	INPP5J	up-regulates	hsa-mir-488	represses	R-356	19	10	Drugs (108) Regulator Drugs (0) Regulon Drugs (108) PF-04691502, UMBRALISIB, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, CSL-324, HYDROXYCHLOROQUINE, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, BMS-986142, HM-71224, NEMIRALISIB, RP-6530, APITOLISIB, AME-133V, DS-7423, GSK-2269557, L19IL2, INCB-40093, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, PF-06651600, AMY-101, LIPEGFILGRASTIM, ABIVERTINIB, VRC-01LS, ABIVERTINIB MALEATE, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, EFALIZUMAB, DACTOLISIB, FILGRASTIM, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, RILZABRUTINIB, BALUGRASTIM, SPEBRUTINIB, PILARALISIB, TASELISIB, L19SIP 131I, AMG-319, IBRUTINIB, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, ZANUBRUTINIB, FIMEPINOSTAT, SATRALIZUMAB, EVOBRUTINIB, CPG-52852, IMIQUIMOD, IC14, TREGALIZUMAB, ERITORAN TETRASODIUM, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, LENOGRASTIM, POSELTINIB, LIFITEGRAST, VB-201, ACALISIB, ZANOLIMUMAB, GSK-2245035, VELIFLAPON, PIRTOBRUTINIB, TELRATOLIMOD, IBALIZUMAB, OCRIPLASMIN, CAL-263, UB-421, ACALABRUTINIB, ERITORAN, ELSUBRUTINIB, BRANEBRUTINIB, LENIOLISIB, PA-799, TIRABRUTINIB, FENEBRUTINIB, LEVILIMAB, GSK-1059615, PEGFILGRASTIM, BUPARLISIB, VESENCUMAB, SF-1126, ORELABRUTINIB, FIBOFLAPON, AL-78898A, PANULISIB
CMF-39324	INPP5J	up-regulates	hsa-mir-488	represses	R-259	19	10	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-39325	INPP5J	up-regulates	hsa-mir-488	represses	R-2767	19	10	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-39326	INPP5J	up-regulates	hsa-mir-488	represses	R-3348	19	10	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-39327	INPP5J	up-regulates	hsa-mir-488	represses	R-1358	19	10	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-39328	INPP5J	up-regulates	hsa-mir-488	represses	R-1829	19	10	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-39528	NF1	down-regulates	hsa-mir-488	represses	R-158	19	12	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, UMBRALISIB, FIBOFLAPON SODIUM, ATN-161, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, VICRIVIROC, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, PILARALISIB, ILORASERTIB, PREXIGEBERSEN, TASELISIB, L19SIP 131I, AMG-319, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, CAFFEINE, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, ADENOSINE, VB-201, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, MILATUZUMAB, VOLOCIXIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, LINTUZUMAB, LEVILIMAB, GSK-1059615, BUPARLISIB, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, FIBOFLAPON, ENMD-981693, PANULISIB, NELFINAVIR
CMF-39529	NF1	down-regulates	hsa-mir-488	represses	R-246	19	12	Drugs (63) Regulator Drugs (0) Regulon Drugs (63) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, DS-7423, GSK-2269557, INCB-40093, PAXALISIB, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, DUVELISIB, DACTOLISIB, ZANDELISIB, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, CERTOLIZUMAB PEGOL, TASELISIB, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, FIMEPINOSTAT, REMTOLUMAB, DUPILUMAB, ACALISIB, CAL-263, ADALIMUMAB, VOLOCIXIMAB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB
CMF-39530	NF1	down-regulates	hsa-mir-488	represses	R-257	19	12	Drugs (149) Regulator Drugs (0) Regulon Drugs (149) PF-04691502, FOSTAMATINIB DISODIUM, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, ONERCEPT, R-343, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, ABATACEPT, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, R-348, AMY-101, PEGSUNERCEPT, GOLIMUMAB, VICRIVIROC, CAFFEINE, CITRATED, MEDI-2338, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, CERDULATINIB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, BOSUTINIB, BAFETINIB, ZANDELISIB, HMPL-523, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, TASELISIB, JNJ-26483327, L19SIP 131I, AMG-319, UCN-01, TADEKINIG ALFA, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, FIMEPINOSTAT, ENTOSPLETINIB, SATRALIZUMAB, CPG-52852, SELGANTOLIMOD, R-333, IMIQUIMOD, GUSACITINIB, REMTOLUMAB, TOLIMIDONE, CAFFEINE, MOTOLIMOD, TOMIVOSERTIB, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, PEGCETACOPLAN, VICRIVIROC MALEATE, ADENOSINE, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, MIVAVOTINIB CITRATE, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, MILATUZUMAB, FOSTAMATINIB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, LINTUZUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, BUPARLISIB, VESENCUMAB, GSK-690693, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, GSK-1070806, FIBOFLAPON, AL-78898A, ENMD-981693, PANULISIB
CMF-39531	NF1	down-regulates	hsa-mir-488	represses	R-290	19	12	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-39532	NF1	down-regulates	hsa-mir-488	represses	R-356	19	12	Drugs (108) Regulator Drugs (0) Regulon Drugs (108) PF-04691502, UMBRALISIB, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, CSL-324, HYDROXYCHLOROQUINE, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, BMS-986142, HM-71224, NEMIRALISIB, RP-6530, APITOLISIB, AME-133V, DS-7423, GSK-2269557, L19IL2, INCB-40093, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, PF-06651600, AMY-101, LIPEGFILGRASTIM, ABIVERTINIB, VRC-01LS, ABIVERTINIB MALEATE, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, EFALIZUMAB, DACTOLISIB, FILGRASTIM, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, RILZABRUTINIB, BALUGRASTIM, SPEBRUTINIB, PILARALISIB, TASELISIB, L19SIP 131I, AMG-319, IBRUTINIB, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, ZANUBRUTINIB, FIMEPINOSTAT, SATRALIZUMAB, EVOBRUTINIB, CPG-52852, IMIQUIMOD, IC14, TREGALIZUMAB, ERITORAN TETRASODIUM, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, LENOGRASTIM, POSELTINIB, LIFITEGRAST, VB-201, ACALISIB, ZANOLIMUMAB, GSK-2245035, VELIFLAPON, PIRTOBRUTINIB, TELRATOLIMOD, IBALIZUMAB, OCRIPLASMIN, CAL-263, UB-421, ACALABRUTINIB, ERITORAN, ELSUBRUTINIB, BRANEBRUTINIB, LENIOLISIB, PA-799, TIRABRUTINIB, FENEBRUTINIB, LEVILIMAB, GSK-1059615, PEGFILGRASTIM, BUPARLISIB, VESENCUMAB, SF-1126, ORELABRUTINIB, FIBOFLAPON, AL-78898A, PANULISIB
CMF-39533	NF1	down-regulates	hsa-mir-488	represses	R-1459	19	12	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-39534	NF1	down-regulates	hsa-mir-488	represses	R-2016	19	12	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-39535	NF1	down-regulates	hsa-mir-488	represses	R-259	19	12	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-39536	NF1	down-regulates	hsa-mir-488	represses	R-2767	19	12	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-39537	NF1	down-regulates	hsa-mir-488	represses	R-3348	19	12	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-39538	NF1	down-regulates	hsa-mir-488	represses	R-1358	19	12	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-39539	NF1	down-regulates	hsa-mir-488	represses	R-1829	19	12	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-39880	ACTL9	down-regulates	hsa-mir-488	represses	R-2016	19	1	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-40116	POTEG	down-regulates	hsa-mir-488	represses	R-290	19	1	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-40643	IDH1	up-regulates	hsa-mir-488	represses	R-2224	19	14	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40644	IDH1	up-regulates	hsa-mir-488	represses	R-2402	19	14	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40645	IDH1	up-regulates	hsa-mir-488	represses	R-2446	19	14	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40646	IDH1	up-regulates	hsa-mir-488	represses	R-2837	19	14	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40647	IDH1	up-regulates	hsa-mir-488	represses	R-3143	19	14	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, TOSEDOSTAT, RIBAVIRIN
CMF-40648	IDH1	up-regulates	hsa-mir-488	represses	R-1459	19	14	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40649	IDH1	up-regulates	hsa-mir-488	represses	R-1820	19	14	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40650	IDH1	up-regulates	hsa-mir-488	represses	R-2016	19	14	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-40651	IDH1	up-regulates	hsa-mir-488	represses	R-259	19	14	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-40652	IDH1	up-regulates	hsa-mir-488	represses	R-2767	19	14	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-40653	IDH1	up-regulates	hsa-mir-488	represses	R-3348	19	14	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-40654	IDH1	up-regulates	hsa-mir-488	represses	R-3370	19	14	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-40655	IDH1	up-regulates	hsa-mir-488	represses	R-1358	19	14	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-40656	IDH1	up-regulates	hsa-mir-488	represses	R-1829	19	14	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-41930	FLT3	down-regulates	hsa-mir-488	represses	R-3143	19	2	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, TOSEDOSTAT, RIBAVIRIN
CMF-41931	FLT3	down-regulates	hsa-mir-488	represses	R-2016	19	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-42987	ESRRB	down-regulates	hsa-mir-488	represses	R-2767	19	4	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-42988	ESRRB	down-regulates	hsa-mir-488	represses	R-3348	19	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-42989	ESRRB	down-regulates	hsa-mir-488	represses	R-3370	19	4	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-42990	ESRRB	down-regulates	hsa-mir-488	represses	R-1829	19	4	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-43328	COL3A1	down-regulates	hsa-mir-488	represses	R-2446	19	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-43329	COL3A1	down-regulates	hsa-mir-488	represses	R-2837	19	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-43330	COL3A1	down-regulates	hsa-mir-488	represses	R-1459	19	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB

hsa-mir-488 -

Function

Causal Mechanistic Flows with hsa-mir-488 as Regulator

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