Regulator

Summary of regulator annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

hsa-mir-30b -

Function

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
-		hsa-mir-30b

List of causal flows containing the regulator.

Causal Flows are statistically significant links between putative causal events (somatic mutations, copy number variations, chromosomal translocations, etc.) and the activity levels of regulators and regulons. In the causal flow, a mutation may causally activate or deactivate a downstream regulator which then might up- down-regulates a regulonthat contains genes with similar expression profiles and binding sites.

Causal Mechanistic Flows with hsa-mir-30b as Regulator

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-33918	SDPR	down-regulates	hsa-mir-30b	represses	R-192	9	3	Drugs (56) Regulator Drugs (0) Regulon Drugs (56) LY-2787106, SARGRAMOSTIM, ATN-161, AME-133V, DASATINIB, ABATACEPT, L19IL2, AS-1409, CCR5MAB004, VRC-01LS, VICRIVIROC, VOBARILIZUMAB, CAROTUXIMAB, L19TNFA, APLAVIROC, MARAVIROC, EFALIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, LERONLIMAB, ILORASERTIB, JNJ-26483327, L19SIP 131I, HGS-1025, PF-04605412, SARILUMAB, CENICRIVIROC, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, SATRALIZUMAB, SELGANTOLIMOD, TOLIMIDONE, MAVRILIMUMAB, MOTOLIMOD, TREGALIZUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, BMS-813160, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, LIFITEGRAST, PF-232798, ZANOLIMUMAB, TELRATOLIMOD, AZD5672, IBALIZUMAB, OCRIPLASMIN, UB-421, ERITORAN, VOLOCIXIMAB, LEVILIMAB, ENMD-981693
CMF-33919	SDPR	down-regulates	hsa-mir-30b	represses	R-232	9	3	Drugs (60) Regulator Drugs (0) Regulon Drugs (60) INFLIXIMAB, MIDOSTAURIN, ATN-161, INTERFERON GAMMA-1B, ONERCEPT, BMS-986142, HM-71224, AME-133V, DASATINIB, MSC-2364447, PF-06651600, AMY-101, PEGSUNERCEPT, ABIVERTINIB, GOLIMUMAB, ABIVERTINIB MALEATE, MEDI-2338, EFALIZUMAB, ETANERCEPT, RILZABRUTINIB, AFELIMOMAB, SPEBRUTINIB, SOTRASTAURIN, OZORALIZUMAB, ILORASERTIB, CERTOLIZUMAB PEGOL, UCN-01, IBRUTINIB, TADEKINIG ALFA, PETESICATIB, PF-04605412, ZANUBRUTINIB, XL-228, EVOBRUTINIB, OTLERTUZUMAB, REMTOLUMAB, BI-836826, TG100-801, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, POSELTINIB, LIFITEGRAST, PIRTOBRUTINIB, OCRIPLASMIN, ACALABRUTINIB, ADALIMUMAB, MILATUZUMAB, VOLOCIXIMAB, ELSUBRUTINIB, BRANEBRUTINIB, PLACULUMAB, TIRABRUTINIB, DELCASERTIB, FENEBRUTINIB, NARATUXIMAB EMTANSINE, GSK-690693, ORELABRUTINIB, GSK-1070806, AL-78898A, ENMD-981693
CMF-33920	SDPR	down-regulates	hsa-mir-30b	represses	R-275	9	3	Drugs (29) Regulator Drugs (0) Regulon Drugs (29) RUPATADINE, DASATINIB, ABATACEPT, L19IL2, AS-1409, AMY-101, MEDI-2338, CAROTUXIMAB, L19TNFA, BOSUTINIB, BAFETINIB, ILORASERTIB, DAPANSUTRILE, JNJ-26483327, L19SIP 131I, TADEKINIG ALFA, NEIHULIZUMAB, BELATACEPT, XL-228, SELGANTOLIMOD, TOLIMIDONE, MOTOLIMOD, TG100-801, PEGCETACOPLAN, TELRATOLIMOD, OCRIPLASMIN, GSK-1070806, AL-78898A, ENMD-981693
CMF-34196	KCNH6	up-regulates	hsa-mir-30b	represses	R-411	9	1	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-34913	POTEE	down-regulates	hsa-mir-30b	represses	R-189	9	1	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34928	KIAA1549	down-regulates	hsa-mir-30b	represses	R-189	9	5	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34929	KIAA1549	down-regulates	hsa-mir-30b	represses	R-274	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-34930	KIAA1549	down-regulates	hsa-mir-30b	represses	R-411	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-34931	KIAA1549	down-regulates	hsa-mir-30b	represses	R-2605	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-34932	KIAA1549	down-regulates	hsa-mir-30b	represses	R-1847	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-35351	ATRX	up-regulates	hsa-mir-30b	represses	R-189	9	5	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-35352	ATRX	up-regulates	hsa-mir-30b	represses	R-274	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-35353	ATRX	up-regulates	hsa-mir-30b	represses	R-411	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-35354	ATRX	up-regulates	hsa-mir-30b	represses	R-2605	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-35355	ATRX	up-regulates	hsa-mir-30b	represses	R-1847	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-36040	SLC22A10	down-regulates	hsa-mir-30b	represses	R-411	9	1	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-36374	DIAPH2	up-regulates	hsa-mir-30b	represses	R-192	9	2	Drugs (56) Regulator Drugs (0) Regulon Drugs (56) LY-2787106, SARGRAMOSTIM, ATN-161, AME-133V, DASATINIB, ABATACEPT, L19IL2, AS-1409, CCR5MAB004, VRC-01LS, VICRIVIROC, VOBARILIZUMAB, CAROTUXIMAB, L19TNFA, APLAVIROC, MARAVIROC, EFALIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, LERONLIMAB, ILORASERTIB, JNJ-26483327, L19SIP 131I, HGS-1025, PF-04605412, SARILUMAB, CENICRIVIROC, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, SATRALIZUMAB, SELGANTOLIMOD, TOLIMIDONE, MAVRILIMUMAB, MOTOLIMOD, TREGALIZUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, BMS-813160, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, LIFITEGRAST, PF-232798, ZANOLIMUMAB, TELRATOLIMOD, AZD5672, IBALIZUMAB, OCRIPLASMIN, UB-421, ERITORAN, VOLOCIXIMAB, LEVILIMAB, ENMD-981693
CMF-36375	DIAPH2	up-regulates	hsa-mir-30b	represses	R-275	9	2	Drugs (29) Regulator Drugs (0) Regulon Drugs (29) RUPATADINE, DASATINIB, ABATACEPT, L19IL2, AS-1409, AMY-101, MEDI-2338, CAROTUXIMAB, L19TNFA, BOSUTINIB, BAFETINIB, ILORASERTIB, DAPANSUTRILE, JNJ-26483327, L19SIP 131I, TADEKINIG ALFA, NEIHULIZUMAB, BELATACEPT, XL-228, SELGANTOLIMOD, TOLIMIDONE, MOTOLIMOD, TG100-801, PEGCETACOPLAN, TELRATOLIMOD, OCRIPLASMIN, GSK-1070806, AL-78898A, ENMD-981693
CMF-37232	OR2T6	down-regulates	hsa-mir-30b	represses	R-350	9	1	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) DASATINIB, VOBARILIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, ILORASERTIB, JNJ-26483327, SARILUMAB, XL-228, SATRALIZUMAB, IC14, TOLIMIDONE, ERITORAN TETRASODIUM, TG100-801, VB-201, ERITORAN, MILATUZUMAB, LEVILIMAB, AMG-557, ENMD-981693
CMF-37388	ABCA10	down-regulates	hsa-mir-30b	represses	R-189	9	6	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-37389	ABCA10	down-regulates	hsa-mir-30b	represses	R-232	9	6	Drugs (60) Regulator Drugs (0) Regulon Drugs (60) INFLIXIMAB, MIDOSTAURIN, ATN-161, INTERFERON GAMMA-1B, ONERCEPT, BMS-986142, HM-71224, AME-133V, DASATINIB, MSC-2364447, PF-06651600, AMY-101, PEGSUNERCEPT, ABIVERTINIB, GOLIMUMAB, ABIVERTINIB MALEATE, MEDI-2338, EFALIZUMAB, ETANERCEPT, RILZABRUTINIB, AFELIMOMAB, SPEBRUTINIB, SOTRASTAURIN, OZORALIZUMAB, ILORASERTIB, CERTOLIZUMAB PEGOL, UCN-01, IBRUTINIB, TADEKINIG ALFA, PETESICATIB, PF-04605412, ZANUBRUTINIB, XL-228, EVOBRUTINIB, OTLERTUZUMAB, REMTOLUMAB, BI-836826, TG100-801, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, POSELTINIB, LIFITEGRAST, PIRTOBRUTINIB, OCRIPLASMIN, ACALABRUTINIB, ADALIMUMAB, MILATUZUMAB, VOLOCIXIMAB, ELSUBRUTINIB, BRANEBRUTINIB, PLACULUMAB, TIRABRUTINIB, DELCASERTIB, FENEBRUTINIB, NARATUXIMAB EMTANSINE, GSK-690693, ORELABRUTINIB, GSK-1070806, AL-78898A, ENMD-981693
CMF-37390	ABCA10	down-regulates	hsa-mir-30b	represses	R-274	9	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-37391	ABCA10	down-regulates	hsa-mir-30b	represses	R-411	9	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-37392	ABCA10	down-regulates	hsa-mir-30b	represses	R-2605	9	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-37393	ABCA10	down-regulates	hsa-mir-30b	represses	R-1847	9	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-38794	RERE	down-regulates	hsa-mir-30b	represses	R-411	9	1	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-39263	PGR	down-regulates	hsa-mir-30b	represses	R-189	9	5	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-39264	PGR	down-regulates	hsa-mir-30b	represses	R-274	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-39265	PGR	down-regulates	hsa-mir-30b	represses	R-411	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-39266	PGR	down-regulates	hsa-mir-30b	represses	R-2605	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-39267	PGR	down-regulates	hsa-mir-30b	represses	R-1847	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-39855	OR6C75	down-regulates	hsa-mir-30b	represses	R-232	9	3	Drugs (60) Regulator Drugs (0) Regulon Drugs (60) INFLIXIMAB, MIDOSTAURIN, ATN-161, INTERFERON GAMMA-1B, ONERCEPT, BMS-986142, HM-71224, AME-133V, DASATINIB, MSC-2364447, PF-06651600, AMY-101, PEGSUNERCEPT, ABIVERTINIB, GOLIMUMAB, ABIVERTINIB MALEATE, MEDI-2338, EFALIZUMAB, ETANERCEPT, RILZABRUTINIB, AFELIMOMAB, SPEBRUTINIB, SOTRASTAURIN, OZORALIZUMAB, ILORASERTIB, CERTOLIZUMAB PEGOL, UCN-01, IBRUTINIB, TADEKINIG ALFA, PETESICATIB, PF-04605412, ZANUBRUTINIB, XL-228, EVOBRUTINIB, OTLERTUZUMAB, REMTOLUMAB, BI-836826, TG100-801, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, POSELTINIB, LIFITEGRAST, PIRTOBRUTINIB, OCRIPLASMIN, ACALABRUTINIB, ADALIMUMAB, MILATUZUMAB, VOLOCIXIMAB, ELSUBRUTINIB, BRANEBRUTINIB, PLACULUMAB, TIRABRUTINIB, DELCASERTIB, FENEBRUTINIB, NARATUXIMAB EMTANSINE, GSK-690693, ORELABRUTINIB, GSK-1070806, AL-78898A, ENMD-981693
CMF-39856	OR6C75	down-regulates	hsa-mir-30b	represses	R-275	9	3	Drugs (29) Regulator Drugs (0) Regulon Drugs (29) RUPATADINE, DASATINIB, ABATACEPT, L19IL2, AS-1409, AMY-101, MEDI-2338, CAROTUXIMAB, L19TNFA, BOSUTINIB, BAFETINIB, ILORASERTIB, DAPANSUTRILE, JNJ-26483327, L19SIP 131I, TADEKINIG ALFA, NEIHULIZUMAB, BELATACEPT, XL-228, SELGANTOLIMOD, TOLIMIDONE, MOTOLIMOD, TG100-801, PEGCETACOPLAN, TELRATOLIMOD, OCRIPLASMIN, GSK-1070806, AL-78898A, ENMD-981693
CMF-39857	OR6C75	down-regulates	hsa-mir-30b	represses	R-350	9	3	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) DASATINIB, VOBARILIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, ILORASERTIB, JNJ-26483327, SARILUMAB, XL-228, SATRALIZUMAB, IC14, TOLIMIDONE, ERITORAN TETRASODIUM, TG100-801, VB-201, ERITORAN, MILATUZUMAB, LEVILIMAB, AMG-557, ENMD-981693
CMF-40289	GRIK3	down-regulates	hsa-mir-30b	represses	R-189	9	5	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-40290	GRIK3	down-regulates	hsa-mir-30b	represses	R-274	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40291	GRIK3	down-regulates	hsa-mir-30b	represses	R-411	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40292	GRIK3	down-regulates	hsa-mir-30b	represses	R-2605	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40293	GRIK3	down-regulates	hsa-mir-30b	represses	R-1847	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40305	MUC17	down-regulates	hsa-mir-30b	represses	R-189	9	9	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-40306	MUC17	down-regulates	hsa-mir-30b	represses	R-192	9	9	Drugs (56) Regulator Drugs (0) Regulon Drugs (56) LY-2787106, SARGRAMOSTIM, ATN-161, AME-133V, DASATINIB, ABATACEPT, L19IL2, AS-1409, CCR5MAB004, VRC-01LS, VICRIVIROC, VOBARILIZUMAB, CAROTUXIMAB, L19TNFA, APLAVIROC, MARAVIROC, EFALIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, LERONLIMAB, ILORASERTIB, JNJ-26483327, L19SIP 131I, HGS-1025, PF-04605412, SARILUMAB, CENICRIVIROC, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, SATRALIZUMAB, SELGANTOLIMOD, TOLIMIDONE, MAVRILIMUMAB, MOTOLIMOD, TREGALIZUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, BMS-813160, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, LIFITEGRAST, PF-232798, ZANOLIMUMAB, TELRATOLIMOD, AZD5672, IBALIZUMAB, OCRIPLASMIN, UB-421, ERITORAN, VOLOCIXIMAB, LEVILIMAB, ENMD-981693
CMF-40307	MUC17	down-regulates	hsa-mir-30b	represses	R-232	9	9	Drugs (60) Regulator Drugs (0) Regulon Drugs (60) INFLIXIMAB, MIDOSTAURIN, ATN-161, INTERFERON GAMMA-1B, ONERCEPT, BMS-986142, HM-71224, AME-133V, DASATINIB, MSC-2364447, PF-06651600, AMY-101, PEGSUNERCEPT, ABIVERTINIB, GOLIMUMAB, ABIVERTINIB MALEATE, MEDI-2338, EFALIZUMAB, ETANERCEPT, RILZABRUTINIB, AFELIMOMAB, SPEBRUTINIB, SOTRASTAURIN, OZORALIZUMAB, ILORASERTIB, CERTOLIZUMAB PEGOL, UCN-01, IBRUTINIB, TADEKINIG ALFA, PETESICATIB, PF-04605412, ZANUBRUTINIB, XL-228, EVOBRUTINIB, OTLERTUZUMAB, REMTOLUMAB, BI-836826, TG100-801, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, POSELTINIB, LIFITEGRAST, PIRTOBRUTINIB, OCRIPLASMIN, ACALABRUTINIB, ADALIMUMAB, MILATUZUMAB, VOLOCIXIMAB, ELSUBRUTINIB, BRANEBRUTINIB, PLACULUMAB, TIRABRUTINIB, DELCASERTIB, FENEBRUTINIB, NARATUXIMAB EMTANSINE, GSK-690693, ORELABRUTINIB, GSK-1070806, AL-78898A, ENMD-981693
CMF-40308	MUC17	down-regulates	hsa-mir-30b	represses	R-274	9	9	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40309	MUC17	down-regulates	hsa-mir-30b	represses	R-275	9	9	Drugs (29) Regulator Drugs (0) Regulon Drugs (29) RUPATADINE, DASATINIB, ABATACEPT, L19IL2, AS-1409, AMY-101, MEDI-2338, CAROTUXIMAB, L19TNFA, BOSUTINIB, BAFETINIB, ILORASERTIB, DAPANSUTRILE, JNJ-26483327, L19SIP 131I, TADEKINIG ALFA, NEIHULIZUMAB, BELATACEPT, XL-228, SELGANTOLIMOD, TOLIMIDONE, MOTOLIMOD, TG100-801, PEGCETACOPLAN, TELRATOLIMOD, OCRIPLASMIN, GSK-1070806, AL-78898A, ENMD-981693
CMF-40310	MUC17	down-regulates	hsa-mir-30b	represses	R-350	9	9	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) DASATINIB, VOBARILIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, ILORASERTIB, JNJ-26483327, SARILUMAB, XL-228, SATRALIZUMAB, IC14, TOLIMIDONE, ERITORAN TETRASODIUM, TG100-801, VB-201, ERITORAN, MILATUZUMAB, LEVILIMAB, AMG-557, ENMD-981693
CMF-40311	MUC17	down-regulates	hsa-mir-30b	represses	R-411	9	9	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40312	MUC17	down-regulates	hsa-mir-30b	represses	R-2605	9	9	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40313	MUC17	down-regulates	hsa-mir-30b	represses	R-1847	9	9	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40673	IDH1	up-regulates	hsa-mir-30b	represses	R-189	9	5	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-40674	IDH1	up-regulates	hsa-mir-30b	represses	R-274	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40675	IDH1	up-regulates	hsa-mir-30b	represses	R-411	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40676	IDH1	up-regulates	hsa-mir-30b	represses	R-2605	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-40677	IDH1	up-regulates	hsa-mir-30b	represses	R-1847	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-41810	IQSEC3	up-regulates	hsa-mir-30b	represses	R-189	9	6	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-41811	IQSEC3	up-regulates	hsa-mir-30b	represses	R-274	9	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-41812	IQSEC3	up-regulates	hsa-mir-30b	represses	R-350	9	6	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) DASATINIB, VOBARILIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, ILORASERTIB, JNJ-26483327, SARILUMAB, XL-228, SATRALIZUMAB, IC14, TOLIMIDONE, ERITORAN TETRASODIUM, TG100-801, VB-201, ERITORAN, MILATUZUMAB, LEVILIMAB, AMG-557, ENMD-981693
CMF-41813	IQSEC3	up-regulates	hsa-mir-30b	represses	R-411	9	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-41814	IQSEC3	up-regulates	hsa-mir-30b	represses	R-2605	9	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-41815	IQSEC3	up-regulates	hsa-mir-30b	represses	R-1847	9	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-42844	EPHA8	down-regulates	hsa-mir-30b	represses	R-189	9	5	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-42845	EPHA8	down-regulates	hsa-mir-30b	represses	R-274	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-42846	EPHA8	down-regulates	hsa-mir-30b	represses	R-411	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-42847	EPHA8	down-regulates	hsa-mir-30b	represses	R-2605	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-42848	EPHA8	down-regulates	hsa-mir-30b	represses	R-1847	9	5	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-43248	PROKR2	up-regulates	hsa-mir-30b	represses	R-192	9	4	Drugs (56) Regulator Drugs (0) Regulon Drugs (56) LY-2787106, SARGRAMOSTIM, ATN-161, AME-133V, DASATINIB, ABATACEPT, L19IL2, AS-1409, CCR5MAB004, VRC-01LS, VICRIVIROC, VOBARILIZUMAB, CAROTUXIMAB, L19TNFA, APLAVIROC, MARAVIROC, EFALIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, LERONLIMAB, ILORASERTIB, JNJ-26483327, L19SIP 131I, HGS-1025, PF-04605412, SARILUMAB, CENICRIVIROC, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, SATRALIZUMAB, SELGANTOLIMOD, TOLIMIDONE, MAVRILIMUMAB, MOTOLIMOD, TREGALIZUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, BMS-813160, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, LIFITEGRAST, PF-232798, ZANOLIMUMAB, TELRATOLIMOD, AZD5672, IBALIZUMAB, OCRIPLASMIN, UB-421, ERITORAN, VOLOCIXIMAB, LEVILIMAB, ENMD-981693
CMF-43249	PROKR2	up-regulates	hsa-mir-30b	represses	R-232	9	4	Drugs (60) Regulator Drugs (0) Regulon Drugs (60) INFLIXIMAB, MIDOSTAURIN, ATN-161, INTERFERON GAMMA-1B, ONERCEPT, BMS-986142, HM-71224, AME-133V, DASATINIB, MSC-2364447, PF-06651600, AMY-101, PEGSUNERCEPT, ABIVERTINIB, GOLIMUMAB, ABIVERTINIB MALEATE, MEDI-2338, EFALIZUMAB, ETANERCEPT, RILZABRUTINIB, AFELIMOMAB, SPEBRUTINIB, SOTRASTAURIN, OZORALIZUMAB, ILORASERTIB, CERTOLIZUMAB PEGOL, UCN-01, IBRUTINIB, TADEKINIG ALFA, PETESICATIB, PF-04605412, ZANUBRUTINIB, XL-228, EVOBRUTINIB, OTLERTUZUMAB, REMTOLUMAB, BI-836826, TG100-801, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, POSELTINIB, LIFITEGRAST, PIRTOBRUTINIB, OCRIPLASMIN, ACALABRUTINIB, ADALIMUMAB, MILATUZUMAB, VOLOCIXIMAB, ELSUBRUTINIB, BRANEBRUTINIB, PLACULUMAB, TIRABRUTINIB, DELCASERTIB, FENEBRUTINIB, NARATUXIMAB EMTANSINE, GSK-690693, ORELABRUTINIB, GSK-1070806, AL-78898A, ENMD-981693
CMF-43250	PROKR2	up-regulates	hsa-mir-30b	represses	R-275	9	4	Drugs (29) Regulator Drugs (0) Regulon Drugs (29) RUPATADINE, DASATINIB, ABATACEPT, L19IL2, AS-1409, AMY-101, MEDI-2338, CAROTUXIMAB, L19TNFA, BOSUTINIB, BAFETINIB, ILORASERTIB, DAPANSUTRILE, JNJ-26483327, L19SIP 131I, TADEKINIG ALFA, NEIHULIZUMAB, BELATACEPT, XL-228, SELGANTOLIMOD, TOLIMIDONE, MOTOLIMOD, TG100-801, PEGCETACOPLAN, TELRATOLIMOD, OCRIPLASMIN, GSK-1070806, AL-78898A, ENMD-981693
CMF-43251	PROKR2	up-regulates	hsa-mir-30b	represses	R-350	9	4	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) DASATINIB, VOBARILIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, ILORASERTIB, JNJ-26483327, SARILUMAB, XL-228, SATRALIZUMAB, IC14, TOLIMIDONE, ERITORAN TETRASODIUM, TG100-801, VB-201, ERITORAN, MILATUZUMAB, LEVILIMAB, AMG-557, ENMD-981693
CMF-43336	LRFN2	up-regulates	hsa-mir-30b	represses	R-192	9	4	Drugs (56) Regulator Drugs (0) Regulon Drugs (56) LY-2787106, SARGRAMOSTIM, ATN-161, AME-133V, DASATINIB, ABATACEPT, L19IL2, AS-1409, CCR5MAB004, VRC-01LS, VICRIVIROC, VOBARILIZUMAB, CAROTUXIMAB, L19TNFA, APLAVIROC, MARAVIROC, EFALIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, LERONLIMAB, ILORASERTIB, JNJ-26483327, L19SIP 131I, HGS-1025, PF-04605412, SARILUMAB, CENICRIVIROC, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, SATRALIZUMAB, SELGANTOLIMOD, TOLIMIDONE, MAVRILIMUMAB, MOTOLIMOD, TREGALIZUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, BMS-813160, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, LIFITEGRAST, PF-232798, ZANOLIMUMAB, TELRATOLIMOD, AZD5672, IBALIZUMAB, OCRIPLASMIN, UB-421, ERITORAN, VOLOCIXIMAB, LEVILIMAB, ENMD-981693
CMF-43337	LRFN2	up-regulates	hsa-mir-30b	represses	R-232	9	4	Drugs (60) Regulator Drugs (0) Regulon Drugs (60) INFLIXIMAB, MIDOSTAURIN, ATN-161, INTERFERON GAMMA-1B, ONERCEPT, BMS-986142, HM-71224, AME-133V, DASATINIB, MSC-2364447, PF-06651600, AMY-101, PEGSUNERCEPT, ABIVERTINIB, GOLIMUMAB, ABIVERTINIB MALEATE, MEDI-2338, EFALIZUMAB, ETANERCEPT, RILZABRUTINIB, AFELIMOMAB, SPEBRUTINIB, SOTRASTAURIN, OZORALIZUMAB, ILORASERTIB, CERTOLIZUMAB PEGOL, UCN-01, IBRUTINIB, TADEKINIG ALFA, PETESICATIB, PF-04605412, ZANUBRUTINIB, XL-228, EVOBRUTINIB, OTLERTUZUMAB, REMTOLUMAB, BI-836826, TG100-801, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, POSELTINIB, LIFITEGRAST, PIRTOBRUTINIB, OCRIPLASMIN, ACALABRUTINIB, ADALIMUMAB, MILATUZUMAB, VOLOCIXIMAB, ELSUBRUTINIB, BRANEBRUTINIB, PLACULUMAB, TIRABRUTINIB, DELCASERTIB, FENEBRUTINIB, NARATUXIMAB EMTANSINE, GSK-690693, ORELABRUTINIB, GSK-1070806, AL-78898A, ENMD-981693
CMF-43338	LRFN2	up-regulates	hsa-mir-30b	represses	R-275	9	4	Drugs (29) Regulator Drugs (0) Regulon Drugs (29) RUPATADINE, DASATINIB, ABATACEPT, L19IL2, AS-1409, AMY-101, MEDI-2338, CAROTUXIMAB, L19TNFA, BOSUTINIB, BAFETINIB, ILORASERTIB, DAPANSUTRILE, JNJ-26483327, L19SIP 131I, TADEKINIG ALFA, NEIHULIZUMAB, BELATACEPT, XL-228, SELGANTOLIMOD, TOLIMIDONE, MOTOLIMOD, TG100-801, PEGCETACOPLAN, TELRATOLIMOD, OCRIPLASMIN, GSK-1070806, AL-78898A, ENMD-981693
CMF-43339	LRFN2	up-regulates	hsa-mir-30b	represses	R-350	9	4	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) DASATINIB, VOBARILIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, ILORASERTIB, JNJ-26483327, SARILUMAB, XL-228, SATRALIZUMAB, IC14, TOLIMIDONE, ERITORAN TETRASODIUM, TG100-801, VB-201, ERITORAN, MILATUZUMAB, LEVILIMAB, AMG-557, ENMD-981693

hsa-mir-30b -

Function

Causal Mechanistic Flows with hsa-mir-30b as Regulator

Regulator Drugs (0)

Regulon Drugs (56)

Regulator Drugs (0)

Regulon Drugs (60)

Regulator Drugs (0)

Regulon Drugs (29)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (56)

Regulator Drugs (0)

Regulon Drugs (29)

Regulator Drugs (0)

Regulon Drugs (20)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (60)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (60)

Regulator Drugs (0)

Regulon Drugs (29)

Regulator Drugs (0)

Regulon Drugs (20)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (2)