Regulator

Summary of regulator annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

NFKB1 - nuclear factor kappa B subunit 1

Function

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. The proteasome-mediated process ensures the production of both p50 and p105 and preserves their independent function, although processing of NFKB1/p105 also appears to occur post-translationally. p50 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. In a complex with MAP3K8, NFKB1/p105 represses MAP3K8-induced MAPK signaling; active MAP3K8 is released by proteasome-dependent degradation of NFKB1/p105.

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
4790	ENSG00000109320	NFKB1	P19838

List of causal flows containing the regulator.

Causal Flows are statistically significant links between putative causal events (somatic mutations, copy number variations, chromosomal translocations, etc.) and the activity levels of regulators and regulons. In the causal flow, a mutation may causally activate or deactivate a downstream regulator which then might up- down-regulates a regulonthat contains genes with similar expression profiles and binding sites.

Causal Mechanistic Flows with ENSG00000109320 as Regulator

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-00040	LRP2	up-regulates	NFKB1	activates	R-299	25	5	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-00533	HMCN1	up-regulates	NFKB1	activates	R-297	25	11	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-00537	HMCN1	up-regulates	NFKB1	activates	R-298	25	11	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-00538	HMCN1	up-regulates	NFKB1	activates	R-300	25	11	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-00539	HMCN1	up-regulates	NFKB1	activates	R-294	25	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-00540	HMCN1	up-regulates	NFKB1	activates	R-307	25	11	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-00542	HMCN1	up-regulates	NFKB1	activates	R-292	25	11	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-00543	HMCN1	up-regulates	NFKB1	activates	R-290	25	11	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-01034	ZNF292	down-regulates	NFKB1	activates	R-297	25	7	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-01037	ZNF292	down-regulates	NFKB1	activates	R-298	25	7	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-01038	ZNF292	down-regulates	NFKB1	activates	R-294	25	7	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-01040	ZNF292	down-regulates	NFKB1	activates	R-290	25	7	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-01166	SKAP2	up-regulates	NFKB1	activates	R-290	25	3	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-01167	SKAP2	up-regulates	NFKB1	activates	R-299	25	3	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-01793	TMPRSS15	up-regulates	NFKB1	activates	R-297	25	4	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-01795	TMPRSS15	up-regulates	NFKB1	activates	R-292	25	4	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-02777	DHX30	up-regulates	NFKB1	activates	R-300	25	3	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-02778	DHX30	up-regulates	NFKB1	activates	R-299	25	3	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-03077	LAMA3	down-regulates	NFKB1	activates	R-300	25	2	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-03684	DSP	up-regulates	NFKB1	activates	R-297	25	13	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-03687	DSP	up-regulates	NFKB1	activates	R-302	25	13	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-03692	DSP	up-regulates	NFKB1	activates	R-292	25	13	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-03693	DSP	up-regulates	NFKB1	activates	R-290	25	13	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-03695	DSP	up-regulates	NFKB1	activates	R-299	25	13	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-04505	LAMC3	down-regulates	NFKB1	activates	R-297	25	7	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-04509	LAMC3	down-regulates	NFKB1	activates	R-290	25	7	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-04510	LAMC3	down-regulates	NFKB1	activates	R-299	25	7	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-05851	LGI2	up-regulates	NFKB1	activates	R-302	25	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-08244	KIF4A	down-regulates	NFKB1	activates	R-298	25	8	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-08245	KIF4A	down-regulates	NFKB1	activates	R-300	25	8	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-08247	KIF4A	down-regulates	NFKB1	activates	R-294	25	8	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-08248	KIF4A	down-regulates	NFKB1	activates	R-292	25	8	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-08249	KIF4A	down-regulates	NFKB1	activates	R-290	25	8	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-08250	KIF4A	down-regulates	NFKB1	activates	R-299	25	8	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-08584	FOXR2	down-regulates	NFKB1	activates	R-299	25	3	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-09470	DOCK11	up-regulates	NFKB1	activates	R-300	25	8	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-09474	DOCK11	up-regulates	NFKB1	activates	R-292	25	8	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-09959	FBN1	down-regulates	NFKB1	activates	R-290	25	4	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-10498	LRBA	up-regulates	NFKB1	activates	R-300	25	3	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-11298	RPTN	up-regulates	NFKB1	activates	R-302	25	4	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-11299	RPTN	up-regulates	NFKB1	activates	R-307	25	4	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-11301	RPTN	up-regulates	NFKB1	activates	R-292	25	4	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-12209	GPR98	down-regulates	NFKB1	activates	R-297	25	6	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-12213	GPR98	down-regulates	NFKB1	activates	R-300	25	6	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-12214	GPR98	down-regulates	NFKB1	activates	R-299	25	6	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-12916	HTR3E	down-regulates	NFKB1	activates	R-294	25	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-12918	HTR3E	down-regulates	NFKB1	activates	R-292	25	5	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-13368	FMN1	up-regulates	NFKB1	activates	R-297	25	7	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-13369	FMN1	up-regulates	NFKB1	activates	R-303	25	7	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-13374	FMN1	up-regulates	NFKB1	activates	R-299	25	7	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-14126	CD1D	up-regulates	NFKB1	activates	R-292	25	2	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-14127	CD1D	up-regulates	NFKB1	activates	R-299	25	2	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-14288	STK31	down-regulates	NFKB1	activates	R-303	25	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-14369	ST18	down-regulates	NFKB1	activates	R-302	25	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-14370	ST18	down-regulates	NFKB1	activates	R-299	25	2	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-15250	HCN1	up-regulates	NFKB1	activates	R-299	25	2	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-15348	DSE	up-regulates	NFKB1	activates	R-297	25	4	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-15351	DSE	up-regulates	NFKB1	activates	R-290	25	4	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-15606	DCHS2	up-regulates	NFKB1	activates	R-297	25	8	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-15612	DCHS2	up-regulates	NFKB1	activates	R-292	25	8	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-15613	DCHS2	up-regulates	NFKB1	activates	R-299	25	8	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-15777	GRM3	up-regulates	NFKB1	activates	R-307	25	3	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-15778	GRM3	up-regulates	NFKB1	activates	R-292	25	3	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-15924	OR13C8	down-regulates	NFKB1	activates	R-299	25	4	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-16373	SUSD5	up-regulates	NFKB1	activates	R-297	25	6	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-16374	SUSD5	up-regulates	NFKB1	activates	R-294	25	6	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-16375	SUSD5	up-regulates	NFKB1	activates	R-307	25	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-16377	SUSD5	up-regulates	NFKB1	activates	R-292	25	6	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-16517	OR9G4	down-regulates	NFKB1	activates	R-303	25	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-16654	DNAJC11	up-regulates	NFKB1	activates	R-294	25	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-16655	DNAJC11	up-regulates	NFKB1	activates	R-290	25	3	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-16694	SI	up-regulates	NFKB1	activates	R-292	25	1	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-17130	CDH18	up-regulates	NFKB1	activates	R-299	25	3	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-18281	MEGF8	up-regulates	NFKB1	activates	R-294	25	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-18595	ZNF569	down-regulates	NFKB1	activates	R-297	25	6	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-18596	ZNF569	down-regulates	NFKB1	activates	R-298	25	6	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-18597	ZNF569	down-regulates	NFKB1	activates	R-294	25	6	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-18598	ZNF569	down-regulates	NFKB1	activates	R-307	25	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-18689	MPP7	down-regulates	NFKB1	activates	R-297	25	4	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-18691	MPP7	down-regulates	NFKB1	activates	R-294	25	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-19212	NF1	up-regulates	NFKB1	activates	R-297	25	14	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-19217	NF1	up-regulates	NFKB1	activates	R-298	25	14	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-19219	NF1	up-regulates	NFKB1	activates	R-300	25	14	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-19220	NF1	up-regulates	NFKB1	activates	R-294	25	14	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-19224	NF1	up-regulates	NFKB1	activates	R-290	25	14	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-19225	NF1	up-regulates	NFKB1	activates	R-299	25	14	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-20290	FREM1	up-regulates	NFKB1	activates	R-297	25	3	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-20365	CUX2	up-regulates	NFKB1	activates	R-294	25	7	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-20366	CUX2	up-regulates	NFKB1	activates	R-307	25	7	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-20370	CUX2	up-regulates	NFKB1	activates	R-299	25	7	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-20537	ADCY1	up-regulates	NFKB1	activates	R-300	25	5	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-20538	ADCY1	up-regulates	NFKB1	activates	R-294	25	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-20540	ADCY1	up-regulates	NFKB1	activates	R-292	25	5	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-20655	CYP4B1	up-regulates	NFKB1	activates	R-298	25	5	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-20656	CYP4B1	up-regulates	NFKB1	activates	R-300	25	5	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-20657	CYP4B1	up-regulates	NFKB1	activates	R-294	25	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-20935	KLHL13	up-regulates	NFKB1	activates	R-307	25	2	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-20936	KLHL13	up-regulates	NFKB1	activates	R-299	25	2	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-20991	KRTAP4-7	up-regulates	NFKB1	activates	R-297	25	11	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-20995	KRTAP4-7	up-regulates	NFKB1	activates	R-298	25	11	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-20996	KRTAP4-7	up-regulates	NFKB1	activates	R-300	25	11	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-20997	KRTAP4-7	up-regulates	NFKB1	activates	R-294	25	11	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-21000	KRTAP4-7	up-regulates	NFKB1	activates	R-292	25	11	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-21001	KRTAP4-7	up-regulates	NFKB1	activates	R-299	25	11	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-21308	GRIK3	up-regulates	NFKB1	activates	R-297	25	5	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-21312	GRIK3	up-regulates	NFKB1	activates	R-292	25	5	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-21565	MUC17	up-regulates	NFKB1	activates	R-297	25	9	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-21568	MUC17	up-regulates	NFKB1	activates	R-298	25	9	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-21570	MUC17	up-regulates	NFKB1	activates	R-300	25	9	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-21571	MUC17	up-regulates	NFKB1	activates	R-294	25	9	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-21572	MUC17	up-regulates	NFKB1	activates	R-307	25	9	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-21573	MUC17	up-regulates	NFKB1	activates	R-290	25	9	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-21982	MIB1	down-regulates	NFKB1	activates	R-297	25	1	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-22089	OR2T34	down-regulates	NFKB1	activates	R-297	25	4	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-23330	CCDC132	up-regulates	NFKB1	activates	R-299	25	4	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-24238	OR5K1	up-regulates	NFKB1	activates	R-298	25	1	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-24440	SEMA3C	down-regulates	NFKB1	activates	R-302	25	6	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-24441	SEMA3C	down-regulates	NFKB1	activates	R-300	25	6	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-24444	SEMA3C	down-regulates	NFKB1	activates	R-292	25	6	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-25940	A1CF	down-regulates	NFKB1	activates	R-298	25	2	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-25941	A1CF	down-regulates	NFKB1	activates	R-294	25	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-25983	CTNNA2	up-regulates	NFKB1	activates	R-297	25	2	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-26297	CHGB	up-regulates	NFKB1	activates	R-292	25	4	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-26298	CHGB	up-regulates	NFKB1	activates	R-299	25	4	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-27281	CHD5	up-regulates	NFKB1	activates	R-297	25	6	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) MIDOSTAURIN, DIPYRIDAMOLE, SOTRASTAURIN, UCN-01, DELCASERTIB, GSK-690693
CMF-27283	CHD5	up-regulates	NFKB1	activates	R-294	25	6	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-27285	CHD5	up-regulates	NFKB1	activates	R-292	25	6	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-27286	CHD5	up-regulates	NFKB1	activates	R-290	25	6	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-28054	CELSR3	down-regulates	NFKB1	activates	R-300	25	5	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-28055	CELSR3	down-regulates	NFKB1	activates	R-294	25	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-28205	REPIN1	up-regulates	NFKB1	activates	R-299	25	4	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-29155	AQP10	down-regulates	NFKB1	activates	R-298	25	10	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-29157	AQP10	down-regulates	NFKB1	activates	R-300	25	10	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-29158	AQP10	down-regulates	NFKB1	activates	R-294	25	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, EMRICASAN, RECOMBINANT HUMAN INTERLEUKIN-15
CMF-29160	AQP10	down-regulates	NFKB1	activates	R-292	25	10	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-29161	AQP10	down-regulates	NFKB1	activates	R-299	25	10	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-29578	ESRRB	down-regulates	NFKB1	activates	R-299	25	9	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-29846	ABCC9	up-regulates	NFKB1	activates	R-299	25	6	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-30041	FAM126B	up-regulates	NFKB1	activates	R-302	25	4	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-30042	FAM126B	up-regulates	NFKB1	activates	R-300	25	4	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-30043	FAM126B	up-regulates	NFKB1	activates	R-292	25	4	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN
CMF-30177	OR4K13	down-regulates	NFKB1	activates	R-299	25	5	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-31302	CLASS_I_PI3K_SIGNALING_EVENTS	up-regulates	NFKB1	activates	R-290	25	3	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-31631	PDGFR_BETA_SIGNALING_PATHWAY	up-regulates	NFKB1	activates	R-302	25	5	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-31634	PDGFR_BETA_SIGNALING_PATHWAY	up-regulates	NFKB1	activates	R-290	25	5	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-31765	ERBB4_SIGNALING_EVENTS	up-regulates	NFKB1	activates	R-299	25	2	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-32482	CXCR4_MEDIATED_SIGNALING_EVENTS	up-regulates	NFKB1	activates	R-302	25	4	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-32485	CXCR4_MEDIATED_SIGNALING_EVENTS	up-regulates	NFKB1	activates	R-290	25	4	Drugs (110) Regulator Drugs (0) Regulon Drugs (110) PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR
CMF-32868	EPHA2_FORWARD_SIGNALING	up-regulates	NFKB1	activates	R-299	25	1	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-33218	EPHRIN_B_REVERSE_SIGNALING	up-regulates	NFKB1	activates	R-299	25	4	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-33674	BCR_SIGNALING_PATHWAY	up-regulates	NFKB1	activates	R-292	25	2	Drugs (20) Regulator Drugs (0) Regulon Drugs (20) GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN

NFKB1 - nuclear factor kappa B subunit 1

Function

Causal Mechanistic Flows with ENSG00000109320 as Regulator

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Regulon Drugs (110)