Program Pr-142

Genes (39)

ADSS, MAN1A1, LNPEP, GALNT12, TBC1D8B, OSTF1, GATA6, RABGAP1L, TPBG, ITGB5, ERP29, KCNN4, CA9, DKK1, PANX1, FHL2, LGALS8, UAP1, MCTP2, DYRK3, PLOD2, USP25, G6PD, GEM, TPP1, VPS37C, AHNAK2, GCNT1, SLC5A3, ABCC1, ACSL4, EDEM1, SEC61A1, P4HA2, GFPT2, SULF1, CSNK1D, KLHL21, GUSB

Regulons (27)

R-186, R-572, R-724, R-853, R-1075, R-1087, R-1259, R-1290, R-1311, R-1602, R-1685, R-1838, R-1913, R-2003, R-2168, R-2458, R-2627, R-2774, R-2834, R-2893, R-3010, R-3098, R-3129, R-3175, R-3277, R-3565, R-3685

Regulons in program Pr-142

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-186	1.17727	9	10
R-572	2.17166	30	9
R-724	1.56401	14	5
R-853	1.69288	11	6
R-1075	1.7301	11	4
R-1087	1.94462	6	10
R-1259	1.70154	7	25
R-1290	1.7925	8	2
R-1311	1.90665	10	15
R-1602	1.31541	15	5
R-1685	1.72594	10	5
R-1838	1.69529	11	4
R-1913	1.82085	11	10
R-2003	1.89694	9	6
R-2168	1.65339	12	3
R-2458	1.51279	14	7
R-2627	1.54969	14	13
R-2774	1.89883	9	2
R-2834	1.77629	10	4
R-2893	1.49882	14	14
R-3010	2.32423	34	22
R-3098	1.7819	10	16
R-3129	1.6429	13	8
R-3175	2.23929	5	10
R-3277	1.90022	7	8
R-3565	1.21984	10	5
R-3685	1.54969	14	10

Genes in program Pr-142

EnsEMBL Id	Entrez Id	Preferred
ENSG00000035687	159	ADSS
ENSG00000111885	4121	MAN1A1
ENSG00000113441	4012	LNPEP
ENSG00000119514	79695	GALNT12
ENSG00000133138	54885	TBC1D8B
ENSG00000134996	26578	OSTF1
ENSG00000141448	2627	GATA6
ENSG00000152061	9910	RABGAP1L
ENSG00000283085	7162	TPBG
ENSG00000082781	3693	ITGB5
ENSG00000089248	10961	ERP29
ENSG00000104783	3783	KCNN4
ENSG00000107159	768	CA9
ENSG00000107984	22943	DKK1
ENSG00000110218	24145	PANX1
ENSG00000115641	2274	FHL2
ENSG00000116977	3964	LGALS8
ENSG00000117143	6675	UAP1
ENSG00000140563	55784	MCTP2
ENSG00000143479	8444	DYRK3
ENSG00000152952	5352	PLOD2
ENSG00000155313	29761	USP25
ENSG00000160211	2539	G6PD
ENSG00000164949	2669	GEM
ENSG00000166340	1200	TPP1
ENSG00000167987	55048	VPS37C
ENSG00000185567	113146	AHNAK2
ENSG00000187210	2650	GCNT1
ENSG00000198743	6526	SLC5A3
ENSG00000278183	4363	ABCC1
ENSG00000068366	2182	ACSL4
ENSG00000134109	9695	EDEM1
ENSG00000058262	29927	SEC61A1
ENSG00000072682	8974	P4HA2
ENSG00000131459	9945	GFPT2
ENSG00000137573	23213	SULF1
ENSG00000141551	1453	CSNK1D
ENSG00000162413	9903	KLHL21
ENSG00000169919	2990	GUSB

Causal Mechanistic Flows with Program Pr-142

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-01615	MCM6	down-regulates	SIX6	represses	R-3175	4	2	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-01862	DAO	down-regulates	ELF4	activates	R-3010	20	3	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-01972	PCDH9	down-regulates	ELF4	activates	R-3010	20	5	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-04898	ABCC5	up-regulates	FOXD3	represses	R-572	25	7	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-05011	NUP210L	up-regulates	FOXD3	represses	R-572	25	4	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-05033	NUP210L	down-regulates	ELF4	activates	R-3010	20	4	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-05904	BCL6	down-regulates	FOXD3	represses	R-572	25	2	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-06320	MATN4	up-regulates	FOXD3	represses	R-572	25	3	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-07025	ATRX	down-regulates	ELF4	activates	R-3010	20	11	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-08076	TRIM6-TRIM34	down-regulates	ELF4	activates	R-3010	20	3	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-09274	RP1	down-regulates	ELF4	activates	R-3010	20	8	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-10812	KIAA1012	down-regulates	FOXD3	represses	R-572	25	1	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-12327	GPR98	down-regulates	ELF4	activates	R-3010	20	10	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-13259	SULF2	up-regulates	FOXD3	represses	R-572	25	4	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-13277	SULF2	down-regulates	ELF4	activates	R-3010	20	6	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-14116	HEATR7B2	down-regulates	ELF4	activates	R-3010	20	3	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-14621	C1orf177	down-regulates	SIX6	represses	R-3175	4	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-15393	DSE	down-regulates	SIX6	represses	R-3175	4	2	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-15520	RASGRF1	down-regulates	FOXD3	represses	R-572	25	2	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-16665	DNAJC11	down-regulates	SIX6	represses	R-3175	4	2	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-16828	ADAMTS2	up-regulates	ELF4	activates	R-3010	20	3	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-17385	TBC1D8	down-regulates	SIX6	represses	R-3175	4	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-18888	INPP5J	down-regulates	ELF4	activates	R-3010	20	5	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-19253	NF1	down-regulates	FOXD3	represses	R-572	25	8	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-19326	NF1	down-regulates	SIX6	represses	R-3175	4	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-19481	NF1	up-regulates	ELF4	activates	R-3010	20	14	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-19656	RPSAP58	down-regulates	SIX6	represses	R-3175	4	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-20128	TDRD9	down-regulates	SIX6	represses	R-3175	4	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-21016	KRTAP4-7	down-regulates	FOXD3	represses	R-572	25	8	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-21061	KRTAP4-7	up-regulates	ELF4	activates	R-3010	20	8	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-21531	KLHL34	down-regulates	ELF4	activates	R-3010	20	6	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-21693	MUC17	up-regulates	ELF4	activates	R-3010	20	9	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-22158	PDGFRA	down-regulates	ELF4	activates	R-3010	20	1	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-22754	IDH1	down-regulates	ELF4	activates	R-3010	20	11	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-24605	THADA	down-regulates	ELF4	activates	R-3010	20	4	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-25744	CHN2	down-regulates	SIX6	represses	R-3175	4	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-27376	FGD5	down-regulates	ELF4	activates	R-3010	20	2	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-27611	ANKRD36	down-regulates	SIX6	represses	R-3175	4	2	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-29223	AQP10	down-regulates	ELF4	activates	R-3010	20	6	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-29391	PTCHD3	down-regulates	ELF4	activates	R-3010	20	4	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-30643	SALL4	down-regulates	ELF4	activates	R-3010	20	4	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-33963	MCM6	down-regulates	hsa-mir-139	represses	R-572	58	34	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-33968	MCM6	down-regulates	hsa-mir-139	represses	R-3010	58	34	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-34010	MCM6	down-regulates	hsa-mir-129	represses	R-572	155	76	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-34028	MCM6	down-regulates	hsa-mir-129	represses	R-3010	155	76	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-34568	TYK2	up-regulates	hsa-mir-9	represses	R-3010	25	5	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-34735	ABCC5	up-regulates	hsa-mir-139	represses	R-572	58	26	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-34742	ABCC5	up-regulates	hsa-mir-139	represses	R-3010	58	26	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-34819	NUP210L	up-regulates	hsa-mir-9	represses	R-572	25	20	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-34821	NUP210L	up-regulates	hsa-mir-9	represses	R-3010	25	20	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-35224	ATRX	up-regulates	hsa-mir-139	represses	R-572	58	58	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-35234	ATRX	up-regulates	hsa-mir-139	represses	R-3010	58	58	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-35323	ATRX	up-regulates	hsa-mir-551b	represses	R-572	22	17	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-35327	ATRX	up-regulates	hsa-mir-551b	represses	R-3010	22	17	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-35362	ATRX	up-regulates	hsa-mir-98	represses	R-3010	8	8	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-35376	ATRX	up-regulates	hsa-mir-301	represses	R-572	37	32	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-35385	ATRX	up-regulates	hsa-mir-301	represses	R-3010	37	32	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-35572	ATRX	up-regulates	hsa-mir-9	represses	R-572	25	25	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-35574	ATRX	up-regulates	hsa-mir-9	represses	R-3010	25	25	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-36125	FAM47A	up-regulates	hsa-mir-301	represses	R-572	37	1	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-36246	TRIM6-TRIM34	up-regulates	hsa-mir-9	represses	R-572	25	2	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-36247	TRIM6-TRIM34	up-regulates	hsa-mir-9	represses	R-3010	25	2	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-36310	FOXR2	up-regulates	hsa-mir-301	represses	R-572	37	12	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-36315	FOXR2	up-regulates	hsa-mir-301	represses	R-3010	37	12	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-36843	SEMG1	up-regulates	hsa-mir-9	represses	R-572	25	5	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-36845	SEMG1	up-regulates	hsa-mir-9	represses	R-3010	25	5	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-37003	ATF7IP2	down-regulates	hsa-mir-139	represses	R-3010	58	1	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-37016	ATF7IP2	down-regulates	hsa-mir-129	represses	R-3010	155	20	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-37452	HTR3E	up-regulates	hsa-mir-129	represses	R-572	155	71	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-37475	HTR3E	up-regulates	hsa-mir-129	represses	R-3010	155	71	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-37650	NRXN1	down-regulates	hsa-mir-551b	represses	R-572	22	3	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-37652	NRXN1	down-regulates	hsa-mir-551b	represses	R-3010	22	3	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-39110	DNMBP	down-regulates	hsa-mir-139	represses	R-572	58	15	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-39492	NF1	down-regulates	hsa-mir-551b	represses	R-572	22	18	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-39496	NF1	down-regulates	hsa-mir-551b	represses	R-3010	22	18	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-39506	NF1	down-regulates	hsa-mir-153	represses	R-572	62	28	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-39516	NF1	down-regulates	hsa-mir-153	represses	R-3010	62	28	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-39653	NF1	down-regulates	hsa-mir-9	represses	R-572	25	10	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-39655	NF1	down-regulates	hsa-mir-9	represses	R-3010	25	10	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-39746	RPSAP58	down-regulates	hsa-mir-301	represses	R-572	37	12	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-39749	RPSAP58	down-regulates	hsa-mir-301	represses	R-3010	37	12	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-40415	PDGFRA	up-regulates	hsa-mir-9	represses	R-572	25	7	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-40417	PDGFRA	up-regulates	hsa-mir-9	represses	R-3010	25	7	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-40468	IDH1	up-regulates	hsa-mir-139	represses	R-572	58	58	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-40478	IDH1	up-regulates	hsa-mir-139	represses	R-3010	58	58	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-40569	IDH1	up-regulates	hsa-mir-551b	represses	R-572	22	17	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-40573	IDH1	up-regulates	hsa-mir-551b	represses	R-3010	22	17	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-40603	IDH1	up-regulates	hsa-mir-153	represses	R-572	62	62	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-40616	IDH1	up-regulates	hsa-mir-153	represses	R-3010	62	62	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-40684	IDH1	up-regulates	hsa-mir-98	represses	R-3010	8	8	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-40698	IDH1	up-regulates	hsa-mir-301	represses	R-572	37	32	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-40707	IDH1	up-regulates	hsa-mir-301	represses	R-3010	37	32	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-40862	IDH1	up-regulates	hsa-mir-9	represses	R-572	25	25	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-40864	IDH1	up-regulates	hsa-mir-9	represses	R-3010	25	25	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-41861	IQSEC3	up-regulates	hsa-mir-98	represses	R-3010	8	7	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-41875	IQSEC3	up-regulates	hsa-mir-9	represses	R-3010	25	17	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-42105	CARD11	up-regulates	hsa-mir-551b	represses	R-572	22	2	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-42106	CARD11	up-regulates	hsa-mir-551b	represses	R-3010	22	2	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-42107	CARD11	up-regulates	hsa-mir-98	represses	R-3010	8	1	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-42280	NBAS	down-regulates	hsa-mir-301	represses	R-572	37	3	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-42281	NBAS	down-regulates	hsa-mir-301	represses	R-3010	37	3	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-42447	ANKRD36	down-regulates	hsa-mir-9	represses	R-572	25	11	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-42449	ANKRD36	down-regulates	hsa-mir-9	represses	R-3010	25	11	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-42478	SLC22A9	down-regulates	hsa-mir-153	represses	R-572	62	1	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-42639	MYO9B	up-regulates	hsa-mir-129	represses	R-572	155	15	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-42646	MYO9B	up-regulates	hsa-mir-129	represses	R-3010	155	15	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-42771	AQP10	up-regulates	hsa-mir-129	represses	R-3010	155	41	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-42791	AQP10	up-regulates	hsa-mir-301	represses	R-3010	37	10	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB

Program

Pr-142

Program Pr-142

Genes (39)

Regulons (27)

Regulons in program Pr-142

Genes in program Pr-142

Causal Mechanistic Flows with Program Pr-142

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (11)

Regulator Drugs (0)

Regulon Drugs (11)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (11)

Regulator Drugs (0)

Regulon Drugs (11)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (11)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (11)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (11)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (11)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (11)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (9)

Regulator Drugs (0)

Regulon Drugs (1)