Program – gbmMINER Portal

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Program – gbmMINER Portal

Program

Program Pr-111

Genes (42)

ATXN1, UBR4, SETD1B, IGF1R, ZCCHC2, CNNM4, TRIM44, USP32, NCOR2, GRK5, PHF20, RAB3GAP1, ADCY9, NDST2, TMEM184B, HIVEP2, WNK1, MEF2A, PLXNA2, CTTN, CLMN, ARHGEF17, FNBP1, ARHGAP26, KIF3B, SLC4A8, ATXN3, BBS7, EXOC6B, OTUD3, ZNF562, PHC3, BMPR2, BTBD7, FOXJ2, SLC23A2, CABIN1, DNAJC16, ERCC5, FAM102A, PACS1, NAPG

Regulons (29)

R-181, R-684, R-743, R-786, R-879, R-916, R-921, R-963, R-1007, R-1106, R-1131, R-1229, R-1319, R-1560, R-1633, R-1711, R-2181, R-2275, R-2401, R-2518, R-2718, R-2839, R-2848, R-3144, R-3228, R-3361, R-3538, R-3742, R-3759

Regulons in program Pr-111

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-181	0.8007	10	37
R-684	0.507441	10	12
R-743	0.706467	13	19
R-786	1.99905	6	3
R-879	0.428057	8	2
R-916	0.704161	12	10
R-921	1.93375	8	7
R-963	1.62627	7	10
R-1007	2.23017	8	9
R-1106	0.592634	11	4
R-1131	0.910367	15	12
R-1229	-0.76085	11	3
R-1319	1.91034	6	3
R-1560	0.681703	7	5
R-1633	0.862376	15	8
R-1711	0.355651	7	5
R-2181	1.01387	9	11
R-2275	1.82142	6	4
R-2401	0.0237177	8	10
R-2518	0.863129	6	3
R-2718	-0.360432	5	10
R-2839	2.4297	6	7
R-2848	0.354374	9	9
R-3144	2.14386	5	4
R-3228	0.181987	6	6
R-3361	1.62627	7	16
R-3538	1.48923	5	6
R-3742	0.502278	9	2
R-3759	0.278424	6	3

Genes in program Pr-111

EnsEMBL Id	Entrez Id	Preferred
ENSG00000124788	6310	ATXN1
ENSG00000127481	23352	UBR4
ENSG00000139718	23067	SETD1B
ENSG00000140443	3480	IGF1R
ENSG00000141664	54877	ZCCHC2
ENSG00000158158	26504	CNNM4
ENSG00000166326	54765	TRIM44
ENSG00000170832	84669	USP32
ENSG00000196498	9612	NCOR2
ENSG00000198873	2869	GRK5
ENSG00000025293	51230	PHF20
ENSG00000115839	22930	RAB3GAP1
ENSG00000162104	115	ADCY9
ENSG00000166507	8509	NDST2
ENSG00000198792	25829	TMEM184B
ENSG00000010818	3097	HIVEP2
ENSG00000060237	65125	WNK1
ENSG00000068305	4205	MEF2A
ENSG00000076356	5362	PLXNA2
ENSG00000085733	2017	CTTN
ENSG00000165959	79789	CLMN
ENSG00000110237	9828	ARHGEF17
ENSG00000187239	23048	FNBP1
ENSG00000145819	23092	ARHGAP26
ENSG00000101350	9371	KIF3B
ENSG00000050438	9498	SLC4A8
ENSG00000066427	4287	ATXN3
ENSG00000138686	55212	BBS7
ENSG00000144036	23233	EXOC6B
ENSG00000169914	23252	OTUD3
ENSG00000171466	54811	ZNF562
ENSG00000173889	80012	PHC3
ENSG00000204217	659	BMPR2
ENSG00000277222	55727	BTBD7
ENSG00000065970	55810	FOXJ2
ENSG00000089057	9962	SLC23A2
ENSG00000099991	23523	CABIN1
ENSG00000116138	23341	DNAJC16
ENSG00000134899	2073	ERCC5
ENSG00000167106	399665	FAM102A
ENSG00000175115	55690	PACS1
ENSG00000134265	8774	NAPG

Causal Mechanistic Flows with Program Pr-111

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs

CMFlow summary not available

Enrichment summary not available