Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
UAP1 - UDP-N-acetylglucosamine pyrophosphorylase 1
Function
Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 6675 | ENSG00000117143 | UAP1 | Q16222 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1041 | Pr-140 | 1 | 1 | 2 |
| R-1046 | Pr-1 | 1 | 1 | 2 |
| R-1073 | Pr-1 | 1 | 1 | 4 |
| R-1133 | Pr-1 | 1 | 1 | 8 |
| R-1170 | Pr-1 | 1 | 1 | 4 |
| R-1308 | Pr-1 | 1 | 1 | 10 |
| R-1346 | Pr-1 | 1 | 1 | 12 |
| R-1495 | Pr-1 | 1 | 1 | 7 |
| R-1651 | Pr-1 | 1 | 1 | 3 |
| R-167 | Pr-1 | 1 | 1 | 10 |
| R-1818 | Pr-1 | 1 | 1 | 2 |
| R-1912 | Pr-1 | 1 | 1 | 8 |
| R-2053 | Pr-1 | 1 | 1 | 61 |
| R-2322 | Pr-1 | 1 | 1 | 6 |
| R-2620 | Pr-1 | 1 | 1 | 3 |
| R-2811 | Pr-1 | 1 | 1 | 5 |
| R-3010 | Pr-142 | 1 | 1 | 59 |
| R-3016 | Pr-1 | 1 | 1 | 21 |
| R-3213 | Pr-137 | 1 | 1 | 5 |
| R-3563 | Pr-1 | 1 | 1 | 3 |
| R-572 | Pr-142 | 1 | 1 | 39 |
| R-582 | Pr-1 | 1 | 1 | 6 |
| R-632 | Pr-1 | 1 | 1 | 10 |
| R-646 | Pr-140 | 1 | 1 | 51 |
| R-683 | Pr-1 | 1 | 1 | 14 |