Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

TPP2 - tripeptidyl peptidase 2

Function

Cytosolic tripeptidyl-peptidase that releases N-terminal tripeptides from polypeptides and is a component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway (PubMed:25525876, PubMed:30533531). It plays an important role in intracellular amino acid homeostasis (PubMed:25525876). Stimulates adipogenesis (By similarity).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
7174 ENSG00000134900 TPP2 P29144

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1566Pr-59116
R-1706Pr-59119
R-1788Pr-59114
R-2273Pr-60117
R-2374Pr-591113
R-2911Pr-59112
R-2924Pr-60112
R-3285Pr-59118
R-3354Pr-154117
R-3460Pr-59114
R-548Pr-59115
R-627Pr-59118