Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
SQRDL - sulfide quinone oxidoreductase
Function
Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone-10, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro) (PubMed:22852582). It is believed the in vivo electron acceptor is glutathione (PubMed:25225291, PubMed:29715001).
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 58472 | ENSG00000137767 | SQRDL | Q9Y6N5 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-117 | Pr-4 | 1 | 1 | 99 |
| R-1358 | Pr-4 | 1 | 1 | 6 |
| R-1592 | Pr-4 | 1 | 1 | 87 |
| R-1608 | Pr-4 | 1 | 1 | 8 |
| R-1679 | Pr-4 | 1 | 1 | 92 |
| R-1829 | Pr-4 | 1 | 1 | 83 |
| R-1926 | Pr-4 | 1 | 1 | 75 |
| R-2161 | Pr-4 | 1 | 1 | 71 |
| R-2477 | Pr-4 | 1 | 1 | 77 |
| R-2500 | Pr-4 | 1 | 1 | 55 |
| R-2885 | Pr-4 | 1 | 1 | 81 |
| R-3134 | Pr-4 | 1 | 1 | 97 |
| R-3348 | Pr-4 | 1 | 1 | 104 |
| R-3377 | Pr-4 | 1 | 1 | 7 |
| R-359 | Pr-4 | 1 | 1 | 7 |
| R-371 | Pr-4 | 1 | 1 | 74 |
| R-397 | Pr-4 | 1 | 1 | 107 |
| R-419 | Pr-4 | 1 | 1 | 90 |
| R-449 | Pr-4 | 1 | 1 | 10 |
| R-737 | Pr-4 | 1 | 1 | 72 |