Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
SLC7A7 - solute carrier family 7 member 7
Function
Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 9056 | ENSG00000155465 | SLC7A7 | Q9UM01 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-112 | Pr-7 | 1 | 1 | 20 |
| R-117 | Pr-4 | 1 | 1 | 99 |
| R-1358 | Pr-4 | 1 | 1 | 6 |
| R-1401 | Pr-4 | 1 | 1 | 5 |
| R-1518 | Pr-4 | 1 | 1 | 7 |
| R-1592 | Pr-4 | 1 | 1 | 87 |
| R-1679 | Pr-4 | 1 | 1 | 92 |
| R-173 | Pr-7 | 1 | 1 | 34 |
| R-174 | Pr-4 | 1 | 1 | 9 |
| R-1829 | Pr-4 | 1 | 1 | 83 |
| R-1926 | Pr-4 | 1 | 1 | 75 |
| R-207 | Pr-7 | 1 | 1 | 44 |
| R-2123 | Pr-4 | 1 | 1 | 85 |
| R-2161 | Pr-4 | 1 | 1 | 71 |
| R-2456 | Pr-4 | 1 | 1 | 3 |
| R-2477 | Pr-4 | 1 | 1 | 77 |
| R-257 | Pr-7 | 1 | 1 | 56 |
| R-259 | Pr-4 | 1 | 1 | 17 |
| R-2767 | Pr-4 | 1 | 1 | 70 |
| R-2885 | Pr-4 | 1 | 1 | 81 |
| R-290 | Pr-7 | 1 | 1 | 68 |
| R-298 | Pr-4 | 1 | 1 | 11 |
| R-3126 | Pr-4 | 1 | 1 | 11 |
| R-3134 | Pr-4 | 1 | 1 | 97 |
| R-315 | Pr-7 | 1 | 1 | 25 |
| R-326 | Pr-7 | 1 | 1 | 29 |
| R-3345 | Pr-4 | 1 | 1 | 2 |
| R-3348 | Pr-4 | 1 | 1 | 104 |
| R-3364 | Pr-4 | 1 | 1 | 5 |
| R-3377 | Pr-4 | 1 | 1 | 7 |
| R-350 | Pr-7 | 1 | 1 | 95 |
| R-370 | Pr-7 | 1 | 1 | 30 |
| R-371 | Pr-4 | 1 | 1 | 74 |
| R-395 | Pr-7 | 1 | 1 | 44 |
| R-397 | Pr-4 | 1 | 1 | 107 |
| R-413 | Pr-7 | 1 | 1 | 23 |
| R-419 | Pr-4 | 1 | 1 | 90 |
| R-438 | Pr-7 | 1 | 1 | 44 |
| R-737 | Pr-4 | 1 | 1 | 72 |
| R-93 | Pr-7 | 1 | 1 | 17 |