Gene details
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
SLC25A24 - solute carrier family 25 member 24
Function
Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane. Nucleotide transport is inactive when cytosolic calcium levels are low, and is activated by an increase in cytosolic calcium levels. May play a role in protecting cells against oxidative stress-induced cell death, probably by promoting the formation of calcium-phosphate precipitates in the mitochondrial matrix, and thereby buffering calcium levels in the mitochondrial matrix.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 29957 | ENSG00000085491 | SLC25A24 | Q6NUK1 |
Gene Regulons
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1100 | Pr-0 | 1 | 1 | 8 |
| R-114 | Pr-0 | 1 | 1 | 12 |
| R-1300 | Pr-0 | 1 | 1 | 25 |
| R-1356 | Pr-0 | 1 | 1 | 4 |
| R-138 | Pr-0 | 1 | 1 | 7 |
| R-1517 | Pr-0 | 1 | 1 | 10 |
| R-1676 | Pr-0 | 1 | 1 | 13 |
| R-175 | Pr-0 | 1 | 1 | 11 |
| R-1813 | Pr-0 | 1 | 1 | 2 |
| R-1904 | Pr-0 | 1 | 1 | 9 |
| R-1982 | Pr-137 | 1 | 1 | 14 |
| R-209 | Pr-0 | 1 | 1 | 6 |
| R-2113 | Pr-0 | 1 | 1 | 5 |
| R-2452 | Pr-0 | 1 | 1 | 3 |
| R-2539 | Pr-0 | 1 | 1 | 2 |
| R-258 | Pr-0 | 1 | 1 | 9 |
| R-276 | Pr-0 | 1 | 1 | 13 |
| R-2982 | Pr-0 | 1 | 1 | 7 |
| R-3073 | Pr-0 | 1 | 1 | 10 |
| R-3096 | Pr-133 | 1 | 1 | 9 |
| R-3103 | Pr-0 | 1 | 1 | 9 |
| R-3127 | Pr-0 | 1 | 1 | 7 |
| R-3152 | Pr-0 | 1 | 1 | 2 |
| R-3161 | Pr-0 | 1 | 1 | 13 |
| R-357 | Pr-0 | 1 | 1 | 8 |
| R-375 | Pr-0 | 1 | 1 | 9 |
| R-398 | Pr-133 | 1 | 1 | 4 |
| R-418 | Pr-0 | 1 | 1 | 12 |
| R-648 | Pr-0 | 1 | 1 | 7 |
| R-680 | Pr-133 | 1 | 1 | 12 |
| R-848 | Pr-0 | 1 | 1 | 9 |
| R-991 | Pr-0 | 1 | 1 | 7 |