Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

SH2B3 - SH2B adaptor protein 3

Function

Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
10019 ENSG00000111252 SH2B3 Q9UQQ2

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-112Pr-71120
R-137Pr-71122
R-192Pr-71174
R-207Pr-71144
R-2329Pr-3112
R-246Pr-71178
R-257Pr-71156
R-290Pr-71168
R-315Pr-71125
R-3219Pr-9111
R-326Pr-71129
R-370Pr-71130
R-3773Pr-8118
R-395Pr-71144
R-413Pr-71123