Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

SERPINB6 - serpin family B member 6

Function

May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
5269 ENSG00000124570 SERPINB6 P35237

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1188Pr-20119
R-119Pr-851114
R-1286Pr-85112
R-1906Pr-851124
R-2532Pr-851145
R-2587Pr-31112
R-2981Pr-20115
R-3437Pr-85116