Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
SERPINA1 - serpin family A member 1
Function
Short peptide from AATReversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 5265 | ENSG00000277377 | SERPINA1 | P01009 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-108 | Pr-7 | 1 | 1 | 9 |
| R-112 | Pr-7 | 1 | 1 | 20 |
| R-117 | Pr-4 | 1 | 1 | 99 |
| R-1401 | Pr-4 | 1 | 1 | 5 |
| R-1592 | Pr-4 | 1 | 1 | 87 |
| R-173 | Pr-7 | 1 | 1 | 34 |
| R-174 | Pr-4 | 1 | 1 | 9 |
| R-1829 | Pr-4 | 1 | 1 | 83 |
| R-1926 | Pr-4 | 1 | 1 | 75 |
| R-207 | Pr-7 | 1 | 1 | 44 |
| R-2161 | Pr-4 | 1 | 1 | 71 |
| R-2412 | Pr-4 | 1 | 1 | 71 |
| R-2456 | Pr-4 | 1 | 1 | 3 |
| R-246 | Pr-7 | 1 | 1 | 78 |
| R-2500 | Pr-4 | 1 | 1 | 55 |
| R-275 | Pr-7 | 1 | 1 | 66 |
| R-2885 | Pr-4 | 1 | 1 | 81 |
| R-290 | Pr-7 | 1 | 1 | 68 |
| R-2943 | Pr-4 | 1 | 1 | 14 |
| R-298 | Pr-4 | 1 | 1 | 11 |
| R-3126 | Pr-4 | 1 | 1 | 11 |
| R-315 | Pr-7 | 1 | 1 | 25 |
| R-3345 | Pr-4 | 1 | 1 | 2 |
| R-3348 | Pr-4 | 1 | 1 | 104 |
| R-350 | Pr-7 | 1 | 1 | 95 |
| R-356 | Pr-7 | 1 | 1 | 57 |
| R-359 | Pr-4 | 1 | 1 | 7 |
| R-370 | Pr-7 | 1 | 1 | 30 |
| R-371 | Pr-4 | 1 | 1 | 74 |
| R-413 | Pr-7 | 1 | 1 | 23 |
| R-419 | Pr-4 | 1 | 1 | 90 |
| R-438 | Pr-7 | 1 | 1 | 44 |
| R-93 | Pr-7 | 1 | 1 | 17 |