Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
PTGER4 - prostaglandin E receptor 4
Function
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 5734 | ENSG00000171522 | PTGER4 | P35408 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1038 | Pr-3 | 1 | 1 | 2 |
| R-1161 | Pr-3 | 1 | 1 | 3 |
| R-118 | Pr-3 | 1 | 1 | 13 |
| R-1305 | Pr-3 | 1 | 1 | 16 |
| R-1465 | Pr-3 | 1 | 1 | 6 |
| R-1486 | Pr-3 | 1 | 1 | 6 |
| R-162 | Pr-3 | 1 | 1 | 8 |
| R-1646 | Pr-3 | 1 | 1 | 4 |
| R-179 | Pr-3 | 1 | 1 | 11 |
| R-1905 | Pr-3 | 1 | 1 | 12 |
| R-1995 | Pr-3 | 1 | 1 | 9 |
| R-2080 | Pr-3 | 1 | 1 | 8 |
| R-2210 | Pr-3 | 1 | 1 | 2 |
| R-2430 | Pr-3 | 1 | 1 | 9 |
| R-2497 | Pr-3 | 1 | 1 | 7 |
| R-2587 | Pr-3 | 1 | 1 | 12 |
| R-2707 | Pr-3 | 1 | 1 | 10 |
| R-2887 | Pr-3 | 1 | 1 | 14 |
| R-3549 | Pr-3 | 1 | 1 | 8 |
| R-3576 | Pr-3 | 1 | 1 | 4 |
| R-378 | Pr-3 | 1 | 1 | 85 |
| R-420 | Pr-3 | 1 | 1 | 11 |
| R-510 | Pr-3 | 1 | 1 | 4 |
| R-578 | Pr-3 | 1 | 1 | 6 |
| R-700 | Pr-3 | 1 | 1 | 2 |
| R-998 | Pr-3 | 1 | 1 | 88 |