Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

PSME1 - proteasome activator subunit 1

Function

Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
5720 ENSG00000092010 PSME1 Q06323

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-115Pr-951122
R-1446Pr-95119
R-2429Pr-951112
R-2476Pr-951113
R-396Pr-95115
R-416Pr-951116