Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

PPP1R12A - protein phosphatase 1 regulatory subunit 12A

Function

Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
4659 ENSG00000058272 PPP1R12A O14974

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1566Pr-59116
R-1788Pr-59114
R-3460Pr-59114
R-627Pr-59118