Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

PLCG2 - phospholipase C gamma 2

Function

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
5336 ENSG00000197943 PLCG2 P16885

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-112Pr-71120
R-137Pr-71122
R-207Pr-71144
R-370Pr-71130
R-413Pr-71123
R-438Pr-71144