Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

PIK3R5 - phosphoinositide-3-kinase regulatory subunit 5

Function

Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG (By similarity).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
23533 ENSG00000141506 PIK3R5 Q8WYR1

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-112Pr-71120
R-315Pr-71125
R-326Pr-71129
R-370Pr-71130
R-395Pr-71144
R-413Pr-71123
R-97Pr-71144