Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

PARP1 - poly(ADP-ribose) polymerase 1

Function

Poly [ADP-ribose] polymerase 1, processed N-terminusThis cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
142 ENSG00000143799 PARP1 P09874

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows