Gene details
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
NT5E - 5'-nucleotidase ecto
Function
Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate (PubMed:21933152, PubMed:34403084, PubMed:24887587, PubMed:22997138, PubMed:23142347). Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms (PubMed:34403084). Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN (PubMed:21933152, PubMed:34403084, PubMed:24887587, PubMed:22997138, PubMed:23142347).
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 4907 | ENSG00000135318 | NT5E | P21589 |
Gene Regulons
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1099 | Pr-38 | 1 | 1 | 11 |
| R-1144 | Pr-38 | 1 | 1 | 19 |
| R-1210 | Pr-38 | 1 | 1 | 8 |
| R-1239 | Pr-38 | 1 | 1 | 25 |
| R-1568 | Pr-38 | 1 | 1 | 38 |
| R-1590 | Pr-38 | 1 | 1 | 22 |
| R-1611 | Pr-38 | 1 | 1 | 6 |
| R-1772 | Pr-38 | 1 | 1 | 26 |
| R-1830 | Pr-38 | 1 | 1 | 16 |
| R-1873 | Pr-38 | 1 | 1 | 27 |
| R-1884 | Pr-38 | 1 | 1 | 7 |
| R-1950 | Pr-43 | 1 | 1 | 45 |
| R-2021 | Pr-38 | 1 | 1 | 69 |
| R-2394 | Pr-38 | 1 | 1 | 28 |
| R-2453 | Pr-38 | 1 | 1 | 20 |
| R-2655 | Pr-38 | 1 | 1 | 5 |
| R-2685 | Pr-38 | 1 | 1 | 42 |
| R-2768 | Pr-38 | 1 | 1 | 6 |
| R-2801 | Pr-38 | 1 | 1 | 5 |
| R-2861 | Pr-38 | 1 | 1 | 31 |
| R-2944 | Pr-38 | 1 | 1 | 16 |
| R-575 | Pr-38 | 1 | 1 | 39 |
| R-625 | Pr-38 | 1 | 1 | 5 |
| R-650 | Pr-38 | 1 | 1 | 36 |
| R-698 | Pr-38 | 1 | 1 | 26 |
| R-968 | Pr-38 | 1 | 1 | 22 |
| R-993 | Pr-38 | 1 | 1 | 31 |