Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

NR2F2 - nuclear receptor subfamily 2 group F member 2

Function

Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development (PubMed:29478779).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
7026 ENSG00000185551 NR2F2 P24468

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1006Pr-161155
R-1047Pr-161131
R-152Pr-161149
R-1734Pr-161144
R-1890Pr-161124
R-2008Pr-161140
R-2043Pr-161153
R-227Pr-161130
R-2326Pr-161127
R-2441Pr-161141
R-2679Pr-161113
R-2972Pr-161120
R-3061Pr-161116
R-3789Pr-161143