Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot
and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser
is available.
NR1H4 - nuclear receptor subfamily 1 group H member 4
Function
Isoform 4Promotes transcriptional activation of target genes ABCB11/BSEP (inducible by unconjugated CDCA, ACA and DCA), NR0B2/SHP (inducible by unconjugated CDCA, ACA and DCA), SLC51B/OSTB (inducible by unconjugated CDCA and DCA) and FABP6/IBAP; most efficient isoform compared to isoforms 1 to 3; not inducible by taurine- and glycine-amidated CDCA.
Uniprot BrowserEntrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
---|---|---|---|
9971 | ENSG00000012504 | NR1H4 | Q96RI1 |
Gene Regulons
List of regulons containing the gene.
A gene
can be associated with multiple causal flows
as a member of multiple regulons