Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

NAGK - N-acetylglucosamine kinase

Function

Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
55577 ENSG00000124357 NAGK Q9UJ70

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-112Pr-71120
R-137Pr-71122
R-173Pr-71134
R-203Pr-7119
R-207Pr-71144
R-246Pr-71178
R-257Pr-71156
R-290Pr-71168
R-315Pr-71125
R-326Pr-71129
R-350Pr-71195
R-370Pr-71130
R-413Pr-71123
R-438Pr-71144
R-86Pr-71162
R-97Pr-71144