Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

LY96 - lymphocyte antigen 96

Function

Binds bacterial lipopolysaccharide (LPS) (PubMed:17803912, PubMed:17569869). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
23643 ENSG00000154589 LY96 Q9Y6Y9

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-112Pr-71120
R-137Pr-71122
R-173Pr-71134
R-192Pr-71174
R-207Pr-71144
R-254Pr-71118
R-315Pr-71125
R-326Pr-71129
R-350Pr-71195
R-356Pr-71157
R-370Pr-71130
R-395Pr-71144
R-413Pr-71123
R-438Pr-71144
R-444Pr-7116
R-93Pr-71117