Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

LIMK1 - LIM domain kinase 1

Function

Isoform 3Has a dominant negative effect on actin cytoskeletal changes. Required for atypical chemokine receptor ACKR2-induced phosphorylation of cofilin (CFL1).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
3984 ENSG00000106683 LIMK1 P53667

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1992Pr-61151
R-216Pr-61117
R-2535Pr-61116
R-2549Pr-6119