Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

LIF - LIF interleukin 6 family cytokine

Function

LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
3976 ENSG00000128342 LIF P15018

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1005Pr-131111
R-123Pr-131117
R-150Pr-13119
R-2454Pr-13116
R-2533Pr-131119
R-2546Pr-13112
R-2955Pr-131123
R-3572Pr-13119
R-431Pr-131116
R-709Pr-13119