Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
LGALS1 - galectin 1
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 3956 | ENSG00000100097 | LGALS1 | P09382 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1300 | Pr-0 | 1 | 1 | 25 |
| R-1676 | Pr-0 | 1 | 1 | 13 |
| R-1925 | Pr-0 | 1 | 1 | 1 |
| R-209 | Pr-0 | 1 | 1 | 6 |
| R-2113 | Pr-0 | 1 | 1 | 5 |
| R-2317 | Pr-0 | 1 | 1 | 10 |
| R-2348 | Pr-0 | 1 | 1 | 9 |
| R-248 | Pr-0 | 1 | 1 | 7 |
| R-2509 | Pr-0 | 1 | 1 | 9 |
| R-2539 | Pr-0 | 1 | 1 | 2 |
| R-258 | Pr-0 | 1 | 1 | 9 |
| R-276 | Pr-0 | 1 | 1 | 13 |
| R-294 | Pr-0 | 1 | 1 | 19 |
| R-2982 | Pr-0 | 1 | 1 | 7 |
| R-3120 | Pr-0 | 1 | 1 | 8 |
| R-3149 | Pr-0 | 1 | 1 | 7 |
| R-357 | Pr-0 | 1 | 1 | 8 |
| R-375 | Pr-0 | 1 | 1 | 9 |
| R-848 | Pr-0 | 1 | 1 | 9 |
| R-991 | Pr-0 | 1 | 1 | 7 |