Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

JUNB - JunB proto-oncogene, AP-1 transcription factor subunit

Function

Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[GC]TCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity (By similarity).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
3726 ENSG00000171223 JUNB P17275

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1005Pr-131111
R-123Pr-131117
R-1314Pr-131125
R-1451Pr-13115
R-1532Pr-131123
R-185Pr-131116
R-224Pr-131115
R-2454Pr-13116
R-2546Pr-13112
R-2821Pr-13116
R-2955Pr-131123
R-3572Pr-13119
R-406Pr-13112
R-431Pr-131116
R-709Pr-13119