Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
IGFBP5 - insulin like growth factor binding protein 5
Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 3488 | ENSG00000115461 | IGFBP5 | P24593 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1018 | Pr-39 | 1 | 1 | 5 |
| R-1129 | Pr-39 | 1 | 1 | 15 |
| R-1166 | Pr-39 | 1 | 1 | 12 |
| R-1185 | Pr-177 | 1 | 1 | 14 |
| R-121 | Pr-39 | 1 | 1 | 9 |
| R-1253 | Pr-39 | 1 | 1 | 28 |
| R-1285 | Pr-177 | 1 | 1 | 5 |
| R-1490 | Pr-39 | 1 | 1 | 13 |
| R-1571 | Pr-39 | 1 | 1 | 14 |
| R-1597 | Pr-39 | 1 | 1 | 9 |
| R-1707 | Pr-39 | 1 | 1 | 14 |
| R-1790 | Pr-39 | 1 | 1 | 6 |
| R-2002 | Pr-177 | 1 | 1 | 23 |
| R-2300 | Pr-39 | 1 | 1 | 13 |
| R-2362 | Pr-39 | 1 | 1 | 9 |
| R-2690 | Pr-39 | 1 | 1 | 13 |
| R-2722 | Pr-39 | 1 | 1 | 4 |
| R-2817 | Pr-39 | 1 | 1 | 10 |
| R-2845 | Pr-39 | 1 | 1 | 10 |
| R-2914 | Pr-39 | 1 | 1 | 14 |
| R-2929 | Pr-39 | 1 | 1 | 22 |
| R-2964 | Pr-39 | 1 | 1 | 26 |
| R-3056 | Pr-39 | 1 | 1 | 22 |
| R-3106 | Pr-177 | 1 | 1 | 10 |
| R-3292 | Pr-39 | 1 | 1 | 4 |
| R-3683 | Pr-39 | 1 | 1 | 20 |
| R-3697 | Pr-39 | 1 | 1 | 32 |
| R-426 | Pr-39 | 1 | 1 | 20 |
| R-556 | Pr-39 | 1 | 1 | 6 |
| R-649 | Pr-6 | 1 | 1 | 13 |
| R-670 | Pr-177 | 1 | 1 | 17 |
| R-702 | Pr-39 | 1 | 1 | 4 |
| R-825 | Pr-39 | 1 | 1 | 9 |
| R-851 | Pr-39 | 1 | 1 | 3 |
| R-873 | Pr-39 | 1 | 1 | 6 |
| R-892 | Pr-177 | 1 | 1 | 2 |
| R-974 | Pr-39 | 1 | 1 | 5 |