Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
IFNGR2 - interferon gamma receptor 2
Function
Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:8124716, PubMed:7673114, PubMed:7615558). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:8124716, PubMed:7673114, PubMed:15356148). Required for signal transduction in contrast to other receptor subunit responsible for ligand binding (PubMed:7673114).
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 3460 | ENSG00000262795 | IFNGR2 | P38484 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1068 | Pr-0 | 1 | 1 | 4 |
| R-1100 | Pr-0 | 1 | 1 | 8 |
| R-1300 | Pr-0 | 1 | 1 | 25 |
| R-1517 | Pr-0 | 1 | 1 | 10 |
| R-175 | Pr-0 | 1 | 1 | 11 |
| R-1904 | Pr-0 | 1 | 1 | 9 |
| R-209 | Pr-0 | 1 | 1 | 6 |
| R-2113 | Pr-0 | 1 | 1 | 5 |
| R-2317 | Pr-0 | 1 | 1 | 10 |
| R-2348 | Pr-0 | 1 | 1 | 9 |
| R-2358 | Pr-0 | 1 | 1 | 11 |
| R-2426 | Pr-137 | 1 | 1 | 92 |
| R-2452 | Pr-0 | 1 | 1 | 3 |
| R-2498 | Pr-0 | 1 | 1 | 17 |
| R-2539 | Pr-0 | 1 | 1 | 2 |
| R-258 | Pr-0 | 1 | 1 | 9 |
| R-2687 | Pr-0 | 1 | 1 | 14 |
| R-2863 | Pr-0 | 1 | 1 | 2 |
| R-294 | Pr-0 | 1 | 1 | 19 |
| R-3073 | Pr-0 | 1 | 1 | 10 |
| R-3103 | Pr-0 | 1 | 1 | 9 |
| R-3120 | Pr-0 | 1 | 1 | 8 |
| R-3127 | Pr-0 | 1 | 1 | 7 |
| R-3149 | Pr-0 | 1 | 1 | 7 |
| R-375 | Pr-0 | 1 | 1 | 9 |
| R-648 | Pr-0 | 1 | 1 | 7 |
| R-680 | Pr-133 | 1 | 1 | 12 |
| R-99 | Pr-0 | 1 | 1 | 13 |
| R-991 | Pr-0 | 1 | 1 | 7 |