Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
ICAM3 - intercellular adhesion molecule 3
Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) (PubMed:1448173). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590).
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 3385 | ENSG00000076662 | ICAM3 | P32942 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1068 | Pr-0 | 1 | 1 | 4 |
| R-1100 | Pr-0 | 1 | 1 | 8 |
| R-114 | Pr-0 | 1 | 1 | 12 |
| R-1300 | Pr-0 | 1 | 1 | 25 |
| R-138 | Pr-0 | 1 | 1 | 7 |
| R-1925 | Pr-0 | 1 | 1 | 1 |
| R-2348 | Pr-0 | 1 | 1 | 9 |
| R-2358 | Pr-0 | 1 | 1 | 11 |
| R-2426 | Pr-137 | 1 | 1 | 92 |
| R-2687 | Pr-0 | 1 | 1 | 14 |
| R-2863 | Pr-0 | 1 | 1 | 2 |
| R-3073 | Pr-0 | 1 | 1 | 10 |
| R-3090 | Pr-0 | 1 | 1 | 6 |
| R-3103 | Pr-0 | 1 | 1 | 9 |
| R-3133 | Pr-0 | 1 | 1 | 8 |
| R-3161 | Pr-0 | 1 | 1 | 13 |
| R-418 | Pr-0 | 1 | 1 | 12 |
| R-648 | Pr-0 | 1 | 1 | 7 |
| R-848 | Pr-0 | 1 | 1 | 9 |
| R-99 | Pr-0 | 1 | 1 | 13 |