Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
F3 - coagulation factor III, tissue factor
Function
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 2152 | ENSG00000117525 | F3 | P13726 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1183 | Pr-43 | 1 | 1 | 26 |
| R-1400 | Pr-85 | 1 | 1 | 8 |
| R-1771 | Pr-43 | 1 | 1 | 1 |
| R-1784 | Pr-43 | 1 | 1 | 11 |
| R-1812 | Pr-43 | 1 | 1 | 5 |
| R-1828 | Pr-43 | 1 | 1 | 11 |
| R-1848 | Pr-43 | 1 | 1 | 8 |
| R-1874 | Pr-20 | 1 | 1 | 7 |
| R-1883 | Pr-43 | 1 | 1 | 7 |
| R-1900 | Pr-43 | 1 | 1 | 7 |
| R-1924 | Pr-43 | 1 | 1 | 3 |
| R-1983 | Pr-172 | 1 | 1 | 20 |
| R-1994 | Pr-43 | 1 | 1 | 24 |
| R-2018 | Pr-43 | 1 | 1 | 11 |
| R-2020 | Pr-20 | 1 | 1 | 33 |
| R-2031 | Pr-43 | 1 | 1 | 15 |
| R-647 | Pr-43 | 1 | 1 | 15 |