Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

F13A1 - coagulation factor XIII A chain

Function

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
2162 ENSG00000124491 F13A1 P00488

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-137Pr-71122
R-173Pr-71134
R-192Pr-71174
R-203Pr-7119
R-232Pr-71177
R-275Pr-71166
R-290Pr-71168
R-326Pr-71129
R-93Pr-71117