Gene – gbmMINER Portal

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Gene – gbmMINER Portal

Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

CLU - clusterin

Function

Isoform 4Does not affect caspase or BAX-mediated intrinsic apoptosis and TNF-induced NF-kappa-B-activity (PubMed:24073260). Promotes cell death through interaction with BCL2L1 that releases and activates BAX (PubMed:21567405).

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
1191	ENSG00000120885	CLU	P10909

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

Regulon	Program	# genes	# regulators	# causal flows