Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

CLEC4A - C-type lectin domain family 4 member A

Function

(Microbial infection) Involved in the interaction between HIV-1 virus and dendritic cells. Enhances HIV-1 binding/entry and virus infection. Requires ITIM motif-associated signal transduction pathway involving phosphatases PTPN6 and PTPN11, SYK, Src kinases and MAP kinases.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
50856 ENSG00000111729 CLEC4A Q9UMR7

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-117Pr-41199
R-1829Pr-41183
R-1926Pr-41175
R-2477Pr-41177
R-3126Pr-41111
R-371Pr-41174
R-419Pr-41190