Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot
and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser
is available.
CBLB - Cbl proto-oncogene B
Function
E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
Uniprot BrowserEntrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
---|---|---|---|
868 | ENSG00000114423 | CBLB | C9K048 |
Gene Regulons
List of regulons containing the gene.
A gene
can be associated with multiple causal flows
as a member of multiple regulons
Regulon | Program | # genes | # regulators | # causal flows |
---|---|---|---|---|
R-1105 | Pr-58 | 1 | 1 | 8 |
R-1147 | Pr-58 | 1 | 1 | 12 |
R-1167 | Pr-58 | 1 | 1 | 6 |
R-1227 | Pr-58 | 1 | 1 | 4 |
R-1270 | Pr-148 | 1 | 1 | 2 |
R-1474 | Pr-58 | 1 | 1 | 7 |
R-1600 | Pr-58 | 1 | 1 | 7 |
R-1632 | Pr-58 | 1 | 1 | 9 |
R-1792 | Pr-58 | 1 | 1 | 1 |
R-2253 | Pr-58 | 1 | 1 | 7 |
R-2757 | Pr-58 | 1 | 1 | 19 |
R-2891 | Pr-58 | 1 | 1 | 5 |
R-303 | Pr-58 | 1 | 1 | 3 |
R-3225 | Pr-58 | 1 | 1 | 4 |
R-3289 | Pr-58 | 1 | 1 | 5 |
R-3339 | Pr-58 | 1 | 1 | 5 |
R-3462 | Pr-58 | 1 | 1 | 12 |
R-3645 | Pr-58 | 1 | 1 | 6 |
R-723 | Pr-58 | 1 | 1 | 14 |