Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
ASCC1 - activating signal cointegrator 1 complex subunit 1
Function
Plays a role in DNA damage repair as component of the ASCC complex (PubMed:29997253). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 51008 | ENSG00000138303 | ASCC1 | Q8N9N2 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons