Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

2-Mar - membrane associated ring-CH-type finger 2

Function

(Microbial infection) Positively regulates the degradation of Vesicular stomatitis virus (VSV) G protein via the lysosomal degradation pathway (PubMed:29573664). Represses HIV-1 viral production and may inhibit the translocation of HIV-1 env to the cell surface, resulting in decreased viral cell-cell transmission (PubMed:29573664).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
51257 ENSG00000099785 2-Mar Q9P0N8

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-112Pr-71120
R-173Pr-71134
R-207Pr-71144
R-315Pr-71125
R-370Pr-71130
R-413Pr-71123
R-86Pr-71162
R-97Pr-71144