Regulon

Regulon: R-376

Regulons are regulatory units consisting of a coherently expressed set of genes and the associated regulator(s) whose binding site(s) they share.

Regulon Summary

Regulon summary table displays all associated information related to the specific regulon including the number of genes in the regulon, Hazard ratio, its Regulator, the Transcriptional Program that includes the regulon, Drugs that are associated with members of the regulon, together with mechanism of action and class, and enriched hallmarks of cancer if any.

Genes	Cox Hazard Ratio	Regulators	Causal Flows	Transcriptional Programs	Hallmarks
27	2.20904	1	15	Pr-5

Regulon Genes

List of genes that are included in the regulon. These genes have similar expression profiles in subset of patients and they share common binding motif for the Regulator of the regulon. Clicking on the gene name will take you to the gene specific page with more details. Please wait while information is collated from several resources after you click.

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
1265	ENSG00000064666	CNN2	B4DUT8
4638	ENSG00000065534	MYLK	Q15746
5743	ENSG00000073756	PTGS2	P35354
2355	ENSG00000075426	FOSL2	P15408
3162	ENSG00000100292	HMOX1	Q6FH11
857	ENSG00000105974	CAV1	A0A024R757
6461	ENSG00000107338	SHB	Q15464
59	ENSG00000107796	ACTA2	P62736
5997	ENSG00000116741	RGS2	P41220
56944	ENSG00000116774	OLFML3	Q9NRN5
1843	ENSG00000120129	DUSP1	P28562
3553	ENSG00000125538	IL1B	P01584
10457	ENSG00000136235	GPNMB	Q14956
3569	ENSG00000136244	IL6	B4DNV3
3586	ENSG00000136634	IL10	P22301
8792	ENSG00000141655	TNFRSF11A	Q9Y6Q6
6876	ENSG00000149591	TAGLN	Q5U0D2
101	ENSG00000151651	ADAM8	P78325
53918	ENSG00000152684	PELO	Q9BRX2
1836	ENSG00000155850	SLC26A2	P50443
433	ENSG00000161944	ASGR2	P07307
5473	ENSG00000163736	PPBP	P02775
5271	ENSG00000166401	SERPINB8	A0A024R2B1
80176	ENSG00000171621	SPSB1	Q96BD6
5551	ENSG00000180644	PRF1	P14222
51393	ENSG00000187688	TRPV2	Q9Y5S1
5770	ENSG00000196396	PTPN1	P18031

Regulon Drugs

Name	Approved Symbol	Type	Action Type	Mechanism of Action	Max Trial Phase	Max GBM Phase
IBUPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	2
PIRPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
PHENYLBUTAZONE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
SCH-708980	IL10	Antibody	INHIBITOR	Interleukin-10 inhibitor	2	0
CIMICOXIB	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	2	0
ACETAMINOPHEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	2
OXYPHENBUTAZONE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
CELECOXIB	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	2
CANAKINUMAB	IL1B	Antibody	INHIBITOR	Interleukin-1 beta inhibitor	4	0
MELOXICAM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
BROMFENAC SODIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
RILONACEPT	IL1B	Protein	INHIBITOR	Interleukin-1 beta inhibitor	4	0
ACECLOFENAC	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
OLSALAZINE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
LORNOXICAM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
FLURBIPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
DIPYRONE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
FENOPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
APRICOXIB	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	2	0
MEDI-5117	IL6	Antibody	INHIBITOR	Interleukin-6 inhibitor	1	0
GEVOKIZUMAB	IL1B	Antibody	NEGATIVE ALLOSTERIC MODULATOR	Interleukin-1 beta negative allosteric modulator	3	0
NAPROXEN SODIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
DEXKETOPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
PARECOXIB	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
ASPIRIN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	2
ESFLURBIPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	3	0
CLAZAKIZUMAB	IL6	Antibody	INHIBITOR	Interleukin-6 inhibitor	3	0
ALOXIPRIN	PTGS2	Unknown	INHIBITOR	Cyclooxygenase inhibitor	4	0
ETORICOXIB	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
INDOPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
KETOROLAC	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
INDOMETHACIN SODIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
BENZYDAMINE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
LUMIRACOXIB	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
NAPROXEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
DICLOFENAC EPOLAMINE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
OLOKIZUMAB	IL6	Antibody	INHIBITOR	Interleukin-6 inhibitor	3	0
FENOPROFEN CALCIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
MECLOFENAMIC ACID	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
OLSALAZINE SODIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
APAZONE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
NABUMETONE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
ROFECOXIB	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
MESALAMINE	PPARG	Small molecule	AGONIST	Peroxisome proliferator-activated receptor gamma agonist	4	0
SILTUXIMAB	IL6	Antibody	ANTAGONIST	Interleukin-6 inhibitor	4	0
MRA 003 US	IL6	Antibody	INHIBITOR	Interleukin-6 inhibitor	1	0
ACEMETACIN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
PARECOXIB SODIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
IBUPROFEN SODIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
LUTIKIZUMAB	IL1A	Antibody	INHIBITOR	Interleukin-1 beta inhibitor	2	0
BALSALAZIDE DISODIUM	PPARG	Small molecule	INHIBITOR	Arachidonate 5-lipoxygenase inhibitor	4	0
NEPAFENAC	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
DICLOFENAC POTASSIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
IBUPROFEN LYSINE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
PIROXICAM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
ETODOLAC	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
SUPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
PF-04236921	IL6	Antibody	INHIBITOR	Interleukin-6 inhibitor	2	0
SULFASALAZINE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	1
MECLOFENAMATE SODIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
GW-406381	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	3	0
LOXOPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	3	0
DICLOFENAC SODIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
BENZYDAMINE HYDROCHLORIDE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
TOLMETIN SODIUM	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
KETOROLAC TROMETHAMINE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
GLEMBATUMUMAB VEDOTIN	TUBB1	Antibody	BINDING AGENT	Transmembrane glycoprotein NMB binding agent	2	0
DEXIBUPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
SULINDAC	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
KETOPROFEN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
BALSALAZIDE	PPARG	Small molecule	INHIBITOR	Arachidonate 5-lipoxygenase inhibitor	4	0
GLEMBATUMUMAB	GPNMB	Antibody	BINDING AGENT	Transmembrane glycoprotein NMB binding agent	1	0
NAPROXCINOD	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	3	0
TOLMETIN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
DICLOFENAC	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
BISMUTH SUBSALICYLATE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
MEFENAMIC ACID	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
GLAFENINE	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
DIFLUNISAL	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
SIRUKUMAB	IL6	Antibody	INHIBITOR	Interleukin-6 inhibitor	3	0
BROMFENAC	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
NAPROXEN ETEMESIL	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	2	0
INDOMETHACIN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
OXAPROZIN	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase inhibitor	4	0
IGURATIMOD	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	3	0
VALDECOXIB	PTGS2	Small molecule	INHIBITOR	Cyclooxygenase-2 inhibitor	4	0
POLMACOXIB	PTGS2	Small molecule	INHIBITOR	Carbonic anhydrase I inhibitor	3	0
ZILTIVEKIMAB	IL6	Antibody	BINDING AGENT	Interleukin-6 binding agent	2	0

Causal Flows

Causal Flows are statistically significant links between putative causal events (somatic mutations, copy number variations, chromosomal translocations, etc.) and the activity levels of regulators and regulons. In the causal flow a mutation may causally activates or deactivates a downstream regulator which then might up- or down-regulates a regulon that contains genes with similar expression profiles and binding sites.

Causal Mechanistic Flows for Regulon R-376

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-01932	PCDH9	down-regulates	SPI1	activates	R-376	25	11	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-07824	TNK2	down-regulates	SPI1	activates	R-376	25	6	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-10033	ATP8A2	down-regulates	SPI1	activates	R-376	25	13	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-11123	MYO18A	down-regulates	SPI1	activates	R-376	25	7	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-12253	GPR98	down-regulates	SPI1	activates	R-376	25	13	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-13772	ADAMTS8	down-regulates	SPI1	activates	R-376	25	12	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-17957	PRPF40B	down-regulates	SPI1	activates	R-376	25	15	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-18867	INPP5J	down-regulates	SPI1	activates	R-376	25	7	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-21611	MUC17	up-regulates	SPI1	activates	R-376	25	13	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-22138	PDGFRA	down-regulates	SPI1	activates	R-376	25	9	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-24854	NSUN5	down-regulates	SPI1	activates	R-376	25	9	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-27588	ANKRD36	up-regulates	SPI1	activates	R-376	25	8	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-29944	GAS2L2	down-regulates	SPI1	activates	R-376	25	7	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-30468	PROKR2	down-regulates	SPI1	activates	R-376	25	6	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB
CMF-30610	SALL4	down-regulates	SPI1	activates	R-376	25	7	Drugs (88) Regulator Drugs (0) Regulon Drugs (88) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB

Regulon: R-376

Regulon Summary

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Causal Mechanistic Flows for Regulon R-376

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